Side Effects of Hemorrhoid Suppositories: What to Expect

After using hemorrhoid suppositories

Since Monday evening, I have been using a hemorrhoidal suppository.
After using it, I sometimes feel a burning sensation and pain in the anal area.
I stopped using it the night before last, and now there is swelling in the area between the anus and the genitals.
It doesn't hurt when I touch it, and I don't feel any foreign sensation while standing or sitting.
Additionally, the skin around my buttocks, near the sides of the anus, is very dry, and I have developed two small bumps that look like pimples.
Could this be a side effect of the hemorrhoidal suppository? What could be going on?

Niming, 20~29 year old female. Ask Date: 2020/06/21

Dr. Lin Minghui reply Gastroenterology and Hepatology

Hello, the skin around the anus is as delicate as the skin on other parts of the body and can be prone to allergies or irritation, leading to conditions such as eczema, acne, abscesses, and infections.
Hemorrhoidal suppositories are solid dosage forms designed in a finger-like shape to assist patients in inserting them into the rectum to relieve pain and discomfort caused by internal hemorrhoids or anal fissures.
It is generally recommended to lubricate the tip with petroleum jelly or ointment before use and gently insert it at the anal opening.
Hemorrhoidal suppositories are intended to alleviate symptoms of hemorrhoidal inflammation, swelling, heat, and pain.
However, prolonged use should be monitored for thinning and damage to the anal skin, recurrent eczema, and local infections.
Wishing you peace and health! Sincerely, Dr.
Ming-Hui Lin, Attending Physician, Department of Gastroenterology, Taoyuan General Hospital, Ministry of Health and Welfare.

Reply Date: 2020/06/21

More Info

When using hemorrhoid suppositories, it is not uncommon to experience various side effects, including localized irritation, burning sensations, and changes in the skin around the anal area. Based on your description, it seems you have encountered some typical reactions that can occur with the use of these medications.

Common Side Effects of Hemorrhoid Suppositories
1. Irritation and Burning Sensation: Many patients report a burning sensation or irritation after using hemorrhoid suppositories. This can be due to the active ingredients in the suppository, which may cause a mild inflammatory response in sensitive tissues. If the burning sensation persists or worsens, it may be advisable to discontinue use and consult a healthcare provider.

2. Swelling and Inflammation: The swelling you describe in the area between the anus and the genitals could be a result of localized irritation from the suppository. This area is sensitive, and any foreign substance can provoke a reaction. If the swelling is not accompanied by pain or significant discomfort, it may resolve on its own after stopping the medication.

3. Dry Skin and Small Bumps: The dryness of the skin near the anus and the appearance of small bumps can also be side effects of the suppository. Some ingredients in these medications can lead to dryness or irritation of the skin, resulting in a rash or small papules that resemble acne. Maintaining proper hygiene and using a gentle moisturizer may help alleviate these symptoms.

When to Seek Medical Attention
While many side effects are mild and self-limiting, certain symptoms warrant a visit to a healthcare professional:
- Persistent Pain or Discomfort: If you experience ongoing pain or discomfort that does not improve after stopping the suppository, it is essential to seek medical advice.

- Severe Swelling or Changes: If the swelling increases or if you notice any changes in color or texture of the skin, it could indicate an allergic reaction or infection.

- Bleeding: If you notice any bleeding, especially if it is significant or accompanied by pain, you should contact a healthcare provider immediately.

Recommendations
1. Discontinue Use: Since you have already stopped using the suppository, monitor your symptoms closely. Many side effects will resolve on their own once the irritant is removed.

2. Gentle Care: Keep the area clean and dry. You may consider using a mild, fragrance-free soap and avoiding harsh scrubs or wipes that could further irritate the skin.

3. Moisturize: If dryness persists, applying a gentle, hypoallergenic moisturizer may help soothe the skin. Avoid products with strong fragrances or active ingredients that could exacerbate irritation.

4. Consult a Healthcare Provider: If symptoms do not improve within a few days or if you have concerns about the bumps or swelling, it is best to consult a healthcare provider. They can assess your symptoms and determine if further treatment is necessary.

Conclusion
In summary, the symptoms you are experiencing after using hemorrhoid suppositories could be related to the medication itself, particularly if you have sensitive skin or a pre-existing condition such as hemorrhoids. While many side effects are benign and resolve with time, it is crucial to monitor your symptoms and seek medical advice if they persist or worsen. Your healthcare provider can offer guidance tailored to your specific situation and help ensure that you receive appropriate care.

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