Groin Swelling: Is It Related to the HPV Vaccine? - Oncology

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Inguinal swelling?


Due to the enlargement of the groin, a biopsy was performed, and the report indicated non-specific reactive hyperplasia, which is benign and may be caused by viral infection or external factors.
Previously, I received the second dose of the cervical cancer vaccine, and three days later, I began experiencing pulling pain in the groin, along with swelling, which has been painful for a month and is still hurting! Doctor, could this be related to the vaccine? Which specialty should I consult?

Eve, 30~39 year old female. Ask Date: 2020/07/03

Dr. Chen Sirong reply Oncology


Eve / 33 years old / Female, is this a vaccine-related issue? A: Personally, I cannot determine that.
Which department should I consult? A: I recommend that you first see an obstetrician-gynecologist.
If that doesn't work, the OB-GYN should be able to provide you with further advice.
Thank you for your inquiry! Wishing you peace and joy! Taoyuan Hospital, Dr.
Chen Sih-Rong.

Reply Date: 2020/07/03

More Info


When it comes to understanding groin swelling and its potential relationship with the HPV vaccine, it's essential to consider several factors. First, let's clarify what the HPV vaccine is designed to do. The HPV vaccine, such as Gardasil, is primarily intended to prevent infections caused by certain types of human papillomavirus (HPV) that are associated with cervical cancer and other HPV-related diseases. The vaccine is generally well-tolerated, but like any medical intervention, it can have side effects.

In your case, you mentioned that you experienced groin swelling and pain shortly after receiving the second dose of the HPV vaccine. While it is possible for vaccines to cause localized reactions, such as swelling or pain at the injection site, systemic reactions like groin swelling are less common. The report you received from the biopsy indicating a "non-specific reactive hyperplasia" suggests that the swelling is likely due to a benign process, which could be related to a viral infection or other non-viral factors.

It's important to note that the HPV vaccine does not cause HPV infections; rather, it helps prevent them. Therefore, the swelling you are experiencing is unlikely to be a direct result of the vaccine itself. However, it is crucial to consider other potential causes, such as lymphadenopathy (swelling of the lymph nodes), which can occur due to infections, inflammation, or other underlying conditions.

Given your symptoms, it would be advisable to consult with a healthcare provider who specializes in this area. You may want to see a primary care physician or a specialist in infectious diseases or urology. They can perform a thorough evaluation, including a physical examination and possibly additional imaging studies, to determine the underlying cause of your groin swelling and pain.

In summary, while the HPV vaccine is unlikely to be the direct cause of your groin swelling, it is essential to investigate further to rule out other potential causes. Consulting with a healthcare provider will help ensure that you receive appropriate care and management for your symptoms. Additionally, if you have any concerns about the vaccine or its side effects, discussing these with your healthcare provider can provide you with more personalized information and reassurance.

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