Can Genital Herpes Cause Lymph Node Swelling? - Urology

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Can herpes cause lymphadenopathy?


Hello doctor, I recently developed a rash on my genitals and went to the hospital for an examination.
The diagnosis was genital herpes.
After some time, I noticed a swollen lymph node in my groin.
Could this be caused by the herpes?

Mr. Wang, 20~29 year old female. Ask Date: 2021/10/01

Dr. Chen Jiansheng reply Urology


Please seek medical examination.

Reply Date: 2021/10/01

More Info


Genital herpes, caused primarily by the herpes simplex virus type 2 (HSV-2), can indeed lead to lymph node swelling, particularly in the groin area. When the body is infected with the herpes virus, the immune system responds to the infection, which can result in inflammation and swelling of nearby lymph nodes. This is a common response as lymph nodes play a crucial role in the immune system by filtering harmful substances and producing immune cells.

When an individual experiences an outbreak of genital herpes, they may notice symptoms such as painful blisters or sores in the genital area, itching, and discomfort. Alongside these local symptoms, systemic symptoms can also occur, including fever, malaise, and swollen lymph nodes. The lymph nodes in the groin (inguinal lymph nodes) are particularly likely to swell in response to genital infections, including herpes.

The swelling of lymph nodes is typically a sign that the body is fighting off an infection. In the case of genital herpes, the lymph nodes may become enlarged as they work to filter out the virus and produce antibodies to combat the infection. This lymphadenopathy (swelling of lymph nodes) can be tender to the touch and may persist for several days to weeks, depending on the severity of the outbreak and the individual's immune response.

It is important to note that while swollen lymph nodes can indicate an active infection, they can also be a sign of other conditions. If the lymph node swelling persists, increases in size, or is accompanied by other concerning symptoms (such as fever, night sweats, or unexplained weight loss), it is advisable to seek further medical evaluation. A healthcare provider may perform a physical examination, take a detailed medical history, and possibly order additional tests to rule out other potential causes of lymphadenopathy.

In summary, genital herpes can indeed cause lymph node swelling, particularly in the groin area, as part of the body's immune response to the infection. If you are experiencing this symptom, it is a good idea to monitor it and consult with your healthcare provider if you have any concerns or if the swelling does not resolve. They can provide guidance on management and any necessary follow-up care.

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