Facial Bone Asymmetry in Children: Allergies or Fibrous Dysplasia? - Otolaryngology

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One side of the facial cheekbone is elevated?


Hello, doctor.
My child has a history of allergies and frequently experiences mumps.
About a month ago, after drinking milk, I noticed swelling in the left eye.
We were referred to Chang Gung Memorial Hospital's ophthalmology department for examination.
After the examination, it was determined to be an allergic reaction.
My child was prescribed medication from a pediatric clinic, and the swelling in the eye did decrease, but the left eye still appears slightly more swollen compared to the right.

Yesterday, while observing my child's eyes, I noticed that the area around the left zygomatic bone seemed more prominent.
That evening, I gave my child anti-inflammatory medication (as my child often has allergies and a runny nose).
The next morning, it felt like the swelling had decreased somewhat, but there is still a noticeable prominence (though it is not very visible externally).
Last night, we visited a local clinic, and the doctor suggested it could possibly be a "fibrous dysplasia" and recommended a CT scan at a larger hospital.

I would like to ask, doctor, is this really the case? Could it possibly be caused by mumps or sinusitis? A concerned father!

William, 10~19 year old female. Ask Date: 2020/07/10

Dr. Li Jiaxuan reply Otolaryngology


If a 10-year-old child is experiencing symptoms, sinusitis or cellulitis should be considered, as well as the possibility of trauma.
However, if the physician determines it to be a fibrous dysplasia, it may be due to the hardness of the affected area.
It is recommended to have an examination at National Taiwan University Children's Hospital.
Wishing for a safe and healthy outcome.

Reply Date: 2020/07/10

More Info


Facial bone asymmetry in children can be a concerning issue for parents, especially when accompanied by symptoms such as swelling or tenderness. In your case, the child has a history of allergies and recurrent sialadenitis (inflammation of the salivary glands), which can complicate the diagnostic picture.
The swelling around the left eye and the prominence of the left zygomatic bone (cheekbone) could indeed be related to several factors. Allergies can cause localized swelling due to inflammation, and if the child has had a recent allergic reaction, this could explain the asymmetry. Allergic reactions can lead to conditions such as allergic conjunctivitis, which may cause swelling around the eyes.
However, the mention of "fibrous dysplasia" by the physician is significant. Fibrous dysplasia is a bone disorder where normal bone is replaced with fibrous tissue, leading to structural weakness and deformity. It can affect any bone in the body, including the facial bones. In children, fibrous dysplasia can present as asymmetry in the facial structure, and it may be associated with pain or tenderness in the affected area.
The fact that the swelling has improved with anti-inflammatory medication suggests that there may be an inflammatory component to the child's condition. However, the persistence of the asymmetry raises the possibility of an underlying structural issue, such as fibrous dysplasia or another bone lesion.
In terms of differential diagnosis, it is also important to consider other conditions that could cause facial asymmetry. For instance, sinusitis (inflammation of the sinuses) can lead to swelling in the facial region, particularly around the cheeks and eyes. If the child has a history of recurrent sinus infections, this could be a contributing factor. Additionally, trauma or injury to the facial bones could lead to localized swelling and asymmetry.

Given the complexity of the situation, it is advisable to follow through with the recommended imaging studies, such as a CT scan, to obtain a clearer picture of the underlying structures. This will help differentiate between an inflammatory process and a potential bony lesion like fibrous dysplasia.
In summary, while allergies and sinusitis could explain some of the symptoms, the possibility of fibrous dysplasia or another bony abnormality cannot be ruled out without further investigation. It is essential to consult with a pediatric specialist, such as a pediatric otolaryngologist or a pediatric orthopedic surgeon, who can provide a comprehensive evaluation and guide the next steps in management. Early diagnosis and intervention are crucial in managing any potential underlying conditions effectively.

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