Can Chronic Prostatitis Cause Autonomic Nervous System Disorders? - Urology

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Can chronic prostatitis lead to autonomic nervous system dysfunction?


Hello, I have been dealing with chronic prostatitis for a long time.
I have undergone blood tests, urinalysis, urinary flow rate tests, and ultrasounds at the hospital, all of which came back normal.
However, the doctors did not perform a digital rectal examination.
I have visited several major hospitals, and the results were the same.
Currently, I am experiencing symptoms where the urethral opening feels very sensitive, similar to a tingling sensation, and my urine stream splits.
The friction of the glans against my underwear is also very stimulating and sensitive, almost like a nerve stimulation, and sometimes it leads to ejaculation.
I am having difficulty concentrating and experiencing memory decline.
Recently, a doctor suggested that I might have autonomic nervous system dysfunction, but only prescribed anti-inflammatory medication and muscle relaxants, without any nerve-related medications.
After taking the medication, my symptoms remain unchanged.
I am truly at a loss for how to resolve this issue.
Could you please provide some advice or recommend which direction I should pursue for further treatment? Should I consider consulting another specialist related to neurology?

KEVIN, 30~39 year old female. Ask Date: 2020/07/15

Dr. Xu Wencang reply Urology


You can consult a neurologist or psychiatrist for further evaluation and consider trying SSRIs that are used to treat premature ejaculation or depression.

Reply Date: 2020/07/15

More Info


Chronic prostatitis, particularly chronic pelvic pain syndrome (CPPS), can indeed have implications for the autonomic nervous system (ANS). The ANS is responsible for regulating involuntary bodily functions, including heart rate, digestion, and the function of the bladder and prostate. When there is chronic inflammation or irritation in the prostate, it can lead to various symptoms that may overlap with autonomic dysfunction.

In your case, the symptoms you describe—such as sensitivity in the urethra, difficulty with urination, and sensations of discomfort in the genital area—can be indicative of pelvic floor dysfunction, which is often associated with chronic prostatitis. The pelvic floor muscles and the nerves that innervate them are closely linked to the autonomic nervous system. Chronic pain or irritation in the pelvic region can lead to heightened sensitivity and altered nerve signaling, which may manifest as the symptoms you are experiencing.

Additionally, the psychological impact of chronic prostatitis, including anxiety and stress, can further exacerbate autonomic dysfunction. Stress can lead to increased sympathetic nervous system activity, which may worsen symptoms like urinary urgency, frequency, and discomfort. This creates a cycle where physical symptoms lead to psychological distress, which in turn can amplify physical symptoms.

Regarding your treatment, it is essential to address both the physical and psychological aspects of your condition. While anti-inflammatory medications and muscle relaxants can help alleviate some symptoms, they may not address the underlying autonomic dysfunction or the psychological components. It may be beneficial to consider a multidisciplinary approach that includes:
1. Pelvic Floor Physical Therapy: A specialized physical therapist can help you learn exercises to strengthen and relax the pelvic floor muscles, which may alleviate some of your symptoms.

2. Cognitive Behavioral Therapy (CBT): This can help address anxiety and stress related to your condition, potentially improving your overall quality of life and reducing the perception of pain.

3. Neurology Consultation: If autonomic dysfunction is suspected, a neurologist can conduct further evaluations to assess nerve function and determine if there are any underlying neurological issues contributing to your symptoms.

4. Urology Follow-Up: Since you have already seen multiple urologists, it may be worth seeking a second opinion from a specialist who focuses on chronic prostatitis or pelvic pain syndromes. They may offer different treatment options or diagnostic tests that have not yet been considered.

5. Lifestyle Modifications: Regular exercise, stress management techniques, and dietary adjustments can also play a significant role in managing chronic prostatitis symptoms and improving overall well-being.

In summary, chronic prostatitis can indeed be linked to autonomic nervous system disorders, particularly through the interplay of physical symptoms and psychological stress. A comprehensive treatment plan that addresses both aspects may provide the best chance for symptom relief and improved quality of life. If your current treatment is not effective, it is advisable to explore these additional avenues with your healthcare provider.

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