HPV Type 84: Risks and Considerations for Pregnancy and VIN Recurrence - Obstetrics and Gynecology

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HPV type 84 infection


Hello Doctor, four years ago I was diagnosed with VIN3 and underwent surgical excision of the lesion.
Since then, I have had two recurrences: once with VIN2, which was also surgically excised, and the most recent occurrence was VIN1 last September (the doctor advised against treatment at that time because I was pregnant).
In July of this year, I had an HPV test that showed infection with HPV type 84.
I would like to ask the doctor: 1.
Is HPV type 84 related to VIN3, or has the virus that led to VIN3 disappeared? 2.
Can HPV type 84 cause precancerous lesions, or does it lead to warts? 3.
I am currently planning to conceive my second child; should I wait for the virus to clear before trying to conceive? (I am a bit concerned since VIN1 occurred during my last pregnancy).
Thank you, Doctor.

Lucy, 40~49 year old female. Ask Date: 2020/07/26

Dr. Zhang Kunmin reply Obstetrics and Gynecology


There are currently over 200 known genotypes of human papillomavirus (HPV), of which approximately 40 can cause lesions in the genital and anal areas.
HPV type 84 is considered a low-risk type.
Based on your description, it is not possible to confirm whether there has been a recurrence of a previous infection or a new infection.
In general, unless there are severe symptoms, there is no recommendation to wait for the virus to clear before becoming pregnant.
However, the pregnancy process should be monitored in accordance with the judgment of your obstetrician.
Thank you! Wishing you peace and health.
Dr.
Zhang

Reply Date: 2020/07/26

More Info


Human Papillomavirus (HPV) is a complex virus with over 200 known types, categorized into high-risk and low-risk groups based on their potential to cause cancer and other health issues. HPV type 84 is classified as a low-risk type, which means it is less likely to cause serious health problems compared to high-risk types, such as HPV 16 and 18, which are associated with cervical cancer and other malignancies.

1. Relationship Between HPV Type 84 and VIN3:
The relationship between HPV type 84 and Vulvar Intraepithelial Neoplasia (VIN) is not straightforward. VIN, particularly VIN3, is a high-grade lesion that can be associated with high-risk HPV types. Since HPV type 84 is considered low-risk, it is less likely to be directly responsible for the development of VIN3. However, it is important to note that HPV infections can be transient, and the specific type of HPV that may have caused VIN3 could have cleared from your system over time. It is possible that the initial infection was with a high-risk type, which has since resolved, while you now have a low-risk type present.

2. Potential for Cancerous Changes:
HPV type 84 is not known to cause precancerous lesions or warts. Low-risk HPV types typically lead to benign conditions such as genital warts rather than cancer. Therefore, while HPV type 84 is present, it is unlikely to lead to significant health issues like VIN or cervical cancer. However, continuous monitoring and follow-up with your healthcare provider are essential, especially given your history of VIN.

3. Pregnancy Considerations:
Regarding your desire to conceive again, it is generally not necessary to wait for the HPV virus to clear before trying to become pregnant, especially since HPV type 84 is low-risk. Many women with HPV go on to have healthy pregnancies and deliveries. However, it is crucial to maintain regular prenatal care and communicate your HPV status with your obstetrician. They can provide tailored advice and monitor any potential complications related to your history of VIN and current HPV infection.

In summary, while HPV type 84 is present, it is classified as low-risk and is unlikely to cause significant health issues or affect your ability to conceive. Your history of VIN is more concerning, and it is essential to continue regular check-ups to monitor for any recurrence or new lesions. Always consult with your healthcare provider for personalized advice and management based on your specific medical history and circumstances. They can guide you through the process of planning for a healthy pregnancy while managing your HPV status.

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