Impact of Ovarian Cysts and Low TSH on Ovulation and Pregnancy Chances - Obstetrics and Gynecology

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The correlation between ovarian cysts, low TSH levels, and the chances of ovulation and pregnancy?


Hello, doctor.
I am currently under treatment, but I have some questions that I feel uncomfortable asking my current physician, so I would like to consult you.
I experience pain and discomfort during ovulation and menstruation, and I also have contraceptive needs, so I have been taking the contraceptive pill, "Yaz," regularly, stopping for one month after every six months of use.
After my last break, my period has not arrived (my last menstruation was on July 2).
I took medication to induce menstruation in early August, but my period still did not come.
Additionally, I have been experiencing pain in my lower right abdomen, and after a consultation, it was found that I have a 4 cm cyst on my right ovary.
The doctor mentioned that I should follow up in three months and ordered blood tests for hormone levels.
The report indicated that my sex hormones are normal, but my TSH level is low, raising suspicion of hyperthyroidism, so I was referred to an endocrinologist.
The results for T3 and T4 tests are still pending.
I have a few questions I would like to ask you:
1.
Could the fact that I took the contraceptive pill for six months and then stopped for one month be the reason for my anovulation and missed period this time? However, if this were the only issue, the medication to induce menstruation should have been effective, right?
2.
I have had several pregnancy tests during my recent visits, all of which were negative.
The most recent test was on August 18, although my last sexual intercourse was on August 14.
If I have an ovarian cyst, will I still ovulate? What is the likelihood of pregnancy in this situation? Will the pregnancy test on August 28 be accurate?
3.
Although my TSH is low, I have a fast heartbeat, feel hot, and sweat easily, but I have not experienced any weight loss (in fact, I have gained three kilograms in the past month).
Pressing on my neck does not cause pain, which does not seem typical for hyperthyroidism.
If it is not hyperthyroidism, what other conditions could cause low TSH? Could this condition directly or indirectly affect my missed period?
I apologize for the many questions, and I appreciate your time in responding!

Niming, 10~19 year old female. Ask Date: 2020/08/26

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, theoretically, your period should arrive within a week after finishing the birth control pills, and it should also come within a week after taking the menstrual induction medication.
If it doesn't arrive, it is recommended to consult a gynecologist.
It is unlikely that you are pregnant, but for thyroid issues, please consult an endocrinologist.
Wishing you good health.

Reply Date: 2020/08/26

More Info


The relationship between ovarian cysts, low TSH levels, and their impact on ovulation and pregnancy chances is a complex interplay of hormonal balance and reproductive health. Let's break down your concerns and provide a comprehensive understanding of the situation.

1. Impact of Birth Control on Ovulation and Menstrual Cycle: When you take hormonal contraceptives, such as the one you mentioned (likely a combination of estrogen and progestin), they work by suppressing ovulation. After stopping the pill, it can take some time for your body to resume its natural hormonal rhythm. This is known as post-pill amenorrhea, where your menstrual cycle may be delayed or irregular for a few months. The fact that you took the pill for six months and then stopped could indeed contribute to the delay in your menstrual cycle. However, if you took a medication to induce menstruation and it did not work, it may indicate that your body is still adjusting or that there are other underlying issues, such as the presence of an ovarian cyst.

2. Ovarian Cysts and Ovulation: The presence of a 4 cm ovarian cyst can affect ovulation. Cysts can be functional (related to the menstrual cycle) or pathological (abnormal growths). Functional cysts, like follicular or corpus luteum cysts, can sometimes prevent ovulation. If a cyst is large, it may also cause discomfort or pain, as you have experienced. However, it is still possible to ovulate even with a cyst present, depending on its nature and the hormonal environment. Your chances of pregnancy may be affected if ovulation does not occur, but if you are actively trying to conceive, monitoring your ovulation through methods such as ovulation predictor kits or ultrasound can provide more clarity.

3. Low TSH Levels and Thyroid Function: Low TSH (Thyroid Stimulating Hormone) levels can indicate hyperthyroidism, where the thyroid gland is overactive. Symptoms you mentioned, such as a rapid heartbeat, heat intolerance, and sweating, align with hyperthyroid conditions. However, weight gain despite low TSH levels is atypical, as hyperthyroidism usually leads to weight loss. Other potential causes for low TSH could include pituitary disorders or the presence of thyroid hormone resistance. It is crucial to follow up with an endocrinologist to evaluate your thyroid function comprehensively, including T3 and T4 levels, to determine the exact cause of your low TSH and its implications for your menstrual cycle and fertility.

4. Pregnancy Testing and Timing: Regarding your pregnancy test, if you had unprotected intercourse on August 14 and tested negative on August 18, it is possible that you were testing too early. Pregnancy tests are most accurate when taken after a missed period. If your menstrual cycle is irregular, it may be beneficial to wait a few more days and retest, ideally around August 28, as you mentioned. If you continue to have negative results and no menstruation, further evaluation by your healthcare provider is warranted.

5. Overall Health and Fertility: Both ovarian cysts and thyroid function can significantly impact fertility. It is essential to address any hormonal imbalances and monitor the cyst. Regular follow-ups with your gynecologist and endocrinologist will help manage these conditions effectively. Lifestyle factors, such as diet, exercise, and stress management, can also play a role in regulating your menstrual cycle and enhancing fertility.

In conclusion, while your current situation may seem concerning, many women experience similar challenges, and with appropriate medical guidance, it is often possible to achieve a healthy pregnancy. Make sure to keep an open line of communication with your healthcare providers, and do not hesitate to ask questions or express concerns during your visits. Your health and well-being are paramount, and proactive management is key to navigating these issues.

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