HPV Infections: Symptoms, Treatment, and Vaccination Insights - Urology

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Questions about HPV infection and vaccines?


Hello, Doctor:
(1) I discovered a 0.5 cm bump at the base of my penis that looks somewhat like a pimple.
After seeing a doctor, I was informed that it is not possible to determine if it is genital warts just by appearance, and further observation is needed to confirm if it is indeed warts or something else.
The recommendation was to either observe it for now or to apply Wart Del cream to treat the lesion.
My question is, if it turns out to be genital warts, do I have to wait for it to worsen or for more lesions to appear before taking action? Are there more proactive measures I can take to prevent the HPV virus from manifesting symptoms?
(2) If it is indeed HPV, does that mean there is a high likelihood of developing more genital warts in the future? Is it possible to be infected with HPV and only have this one lesion? Would addressing the lesion when it is small help prevent it from spreading, or will it eventually grow regardless?
(3) Is it true that maintaining regular exercise, a positive mindset, and overall good health can increase the chances of not developing genital warts after being infected with HPV? Or once infected with HPV types 6 or 11, is it almost inevitable to develop symptoms?
(4) Additionally, during my visit to the doctor, I inquired about the HPV vaccine.
However, due to the high volume of patients, I couldn't ask further questions, so I would like to consult you.
I understand that the HPV vaccine can only "prevent" and not "treat." Therefore, if my current lesion is indeed caused by an HPV type 6 infection, I understand that receiving the nine-valent vaccine would not be effective against the existing type 6 virus but would prevent the other eight types.
Does this mean that I will never be able to prevent an HPV-6 infection in my lifetime? In other words, if I successfully treat my current HPV-6 infection, or if my immune system clears the HPV-6 over time (is this possible? What are the chances? I've seen conflicting information about whether it can clear or not), will the vaccine still not protect me from reinfection with HPV-6 and the development of genital warts in the future? Thank you, Doctor! I am really anxious because I always use condoms during sexual activity and have been very cautious.
Although I know that condoms do not provide complete protection against genital warts, I still feel very frustrated and scared.

Mars, 30~39 year old female. Ask Date: 2020/09/09

Dr. Du Shixi reply Urology


Hello: 1) It is recommended to undergo a pathological examination.
2) It is possible to have only one lesion; of course, early treatment is advised to prevent infection of the surrounding skin.
3) Good immunity can reduce the risk of infection and also decrease the likelihood of new lesions; the key factors in infection are the viral load and the body's resistance.
4) Prevention is the only option; after a specific type of infection, the body will attempt to clear it on its own, but there is no guarantee that reinfection will not occur in the future.
Condoms cannot completely prevent warts, but they still provide some protection.
Wishing you good health.

Reply Date: 2020/09/09

More Info


Understanding HPV Infections: Symptoms, Treatment, and Vaccination Insights
Human Papillomavirus (HPV) is a common sexually transmitted infection that can lead to various health issues, including genital warts (often referred to as "cauliflower" due to their appearance) and certain types of cancer. Your concerns regarding a potential HPV infection and the associated symptoms are valid and warrant a thorough understanding of the virus, its implications, and the available preventive measures.

1. Observation and Treatment of Symptoms: You mentioned noticing a 0.5 cm bump at the base of your penis that resembles a pimple. While it is prudent to observe the lesion, it is important to consult a healthcare provider for a definitive diagnosis. If it is indeed a wart caused by HPV, there are treatments available, such as topical creams like Wart Del, which can help manage the symptoms. However, it is not necessary to wait for the lesion to worsen before seeking treatment. Early intervention can often prevent the spread of the virus and the development of additional warts.
2. Risk of Additional Warts: If you are diagnosed with HPV, there is a possibility of developing more warts, but this is not guaranteed. Some individuals may only experience a single wart, while others may develop multiple lesions. The presence of one wart does not necessarily indicate that more will appear, but it is crucial to monitor any changes. Early treatment of any visible symptoms can help reduce the likelihood of further outbreaks.

3. Immune System and HPV: Maintaining a healthy lifestyle, including regular exercise and a balanced diet, can bolster your immune system. A strong immune response can help your body manage and potentially clear HPV infections. While some studies suggest that many individuals can clear HPV infections naturally, this varies from person to person. For high-risk types, such as HPV-6 and HPV-11, the likelihood of developing warts may increase if the immune system is compromised. However, it is important to note that even with a healthy lifestyle, some individuals may still experience symptoms.

4. HPV Vaccination: Regarding the HPV vaccine, it is indeed designed to prevent infection from certain strains of the virus, including HPV-6 and HPV-11, but it does not treat existing infections. If you are currently infected with HPV-6, the vaccine will not provide protection against that specific strain. However, if your body successfully clears the infection in the future, the vaccine can still protect you from other HPV strains included in the vaccine. It is important to understand that while the vaccine is highly effective in preventing new infections, it does not eliminate the risk of re-infection from the same strain if you have previously been infected.

In conclusion, while it is understandable to feel anxious about HPV and its potential consequences, proactive management of your health, including regular check-ups and discussions with your healthcare provider, can significantly mitigate risks. If you have concerns about your symptoms or the HPV vaccine, do not hesitate to seek further clarification from your doctor. They can provide personalized advice based on your health history and current situation. Remember, you are not alone in this, and many people navigate similar concerns regarding HPV.

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