Elevated Sperm White Blood Cells: Should You Be Concerned? - Urology

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Regarding elevated white blood cells in semen?


Hello Dr.
Tsai: Recently, my fiancée and I underwent premarital health screening, and the report indicated that my semen white blood cell count is elevated, with a result of 1.
This has caused me some concern, and I would like to ask you how serious this issue is.
Should I be overly worried? Thank you.

Leo, 30~39 year old female. Ask Date: 2020/10/13

Dr. Cai Zhuorong reply Urology


The presence of white blood cells indicates a need to consider infection; however, different laboratories have varying rates of false positives.
It is recommended to seek medical attention and undergo re-examination for confirmation.

Reply Date: 2020/10/13

More Info


Elevated white blood cells (WBCs) in semen, also known as leukocytospermia, can be a concerning finding, especially when it comes to male fertility and overall reproductive health. In your case, the report indicates a count of 1 million white blood cells per milliliter of semen, which is above the normal threshold. While it’s understandable to feel anxious about this result, it’s important to contextualize what elevated WBCs in semen might mean and the steps you can take moving forward.


Understanding Elevated Sperm White Blood Cells
1. What Does It Mean?
Elevated WBCs in semen can indicate an inflammatory response in the male reproductive system. This inflammation may be due to various factors, including infections (such as prostatitis, epididymitis, or sexually transmitted infections), immune responses, or other underlying medical conditions. The presence of white blood cells is part of the body's defense mechanism against infections, so their elevation often suggests that the body is responding to some form of irritation or infection.

2. Potential Implications for Fertility
Research indicates that elevated WBCs in semen can negatively impact sperm quality and motility, which are critical factors for fertility. High levels of leukocytes can lead to oxidative stress, which may damage sperm DNA and affect overall reproductive outcomes. However, the degree of impact can vary significantly from person to person.

3. When to Be Concerned
While an elevated WBC count in semen warrants further investigation, it does not automatically mean that there is a severe problem. It is essential to consider other factors, such as:
- Symptoms: Are you experiencing any pain, discomfort, or unusual symptoms in the genital area?
- Medical History: Do you have a history of urinary tract infections, sexually transmitted infections, or other reproductive health issues?
- Fertility Goals: If you and your fiancée are planning to conceive soon, it may be prudent to address this issue more urgently.


Next Steps
1. Consult a Specialist
It is advisable to consult a urologist or a fertility specialist who can further evaluate your condition. They may recommend additional tests, such as:
- Semen Culture: To identify any underlying infections that may be contributing to the elevated WBC count.

- Blood Tests: To check for systemic infections or other health issues.

- Ultrasound: To visualize the reproductive organs and check for abnormalities.

2. Treatment Options
If an infection is identified, appropriate treatment with antibiotics or other medications may be necessary. If no infection is found, your doctor may suggest lifestyle changes or supplements to improve overall reproductive health.

3. Lifestyle Modifications
Consider adopting a healthy lifestyle that includes:
- Balanced Diet: Rich in antioxidants, vitamins, and minerals that support reproductive health.

- Regular Exercise: To improve circulation and overall health.

- Stress Management: Techniques such as yoga, meditation, or counseling can help reduce stress, which may positively impact fertility.

4. Follow-Up Testing
After any treatment or lifestyle changes, follow-up testing may be necessary to monitor your WBC levels and overall semen quality.


Conclusion
In summary, while an elevated white blood cell count in your semen is a finding that should be taken seriously, it does not necessarily indicate a severe problem. It is essential to follow up with a healthcare professional who can provide a comprehensive evaluation and guide you through the necessary steps. By addressing this issue proactively, you can ensure that you are in the best possible health as you prepare for marriage and family planning. Remember, open communication with your partner about health concerns is also vital as you navigate this journey together.

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