Does Concan Cause Erectile Dysfunction in Heart Patients? - Cardiology

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The patient has a stent in the heart and takes half a tablet of Concor 5 mg daily, one tablet of Lipitor 5/20 mg, and one tablet of Clopidogrel 75/100 mg.
The patient also has high cholesterol and hypertension issues.
Clopidogrel is used for thrombus prevention, while Lipitor is for lowering cholesterol and blood pressure.

The patient asks the doctor: Is Concor primarily for blood pressure management or for the stent (coronary artery disease)? It seems that it addresses both based on its description.
After taking the medication, the patient experiences significant sexual dysfunction (difficulty achieving and maintaining an erection).
The patient notes that Concor may cause sexual side effects.
Are there other medications that can be switched to?

Lao Ma, 40~49 year old female. Ask Date: 2020/10/14

Dr. Wu Xueming reply Cardiology


Kankun is a beta-blocker used for cardiovascular purposes and can also lower blood pressure.
If it affects sexual function, you can discuss with your prescribing physician about switching to another medication.

Reply Date: 2020/10/14

More Info


Concan, known generically as amlodipine, is a calcium channel blocker primarily used to treat high blood pressure and angina (chest pain). It works by relaxing the blood vessels, allowing blood to flow more easily, which can be beneficial for patients with coronary artery disease (CAD) or those who have had stents placed. However, like many medications, it can have side effects, and erectile dysfunction (ED) is one of the potential adverse effects associated with its use.

In patients with heart conditions, particularly those who have undergone procedures like stent placement, the management of blood pressure and heart function is crucial. Amlodipine is often prescribed not only for hypertension but also for its ability to improve blood flow and reduce the workload on the heart. However, the relationship between cardiovascular medications and sexual function is complex.
Erectile dysfunction can be influenced by various factors, including psychological issues, hormonal imbalances, and the side effects of medications. While amlodipine is not the most commonly cited medication for causing ED, it can contribute to this issue in some individuals. The mechanism by which calcium channel blockers might affect erectile function is not entirely understood, but it is believed that they may interfere with the vascular processes necessary for achieving and maintaining an erection.

In your case, since you are experiencing noticeable erectile dysfunction after starting Concan, it is important to discuss this with your healthcare provider. They can evaluate whether the medication is indeed contributing to your symptoms and consider alternative treatments. There are several other classes of medications available for managing high blood pressure and CAD that may have a lower risk of causing erectile dysfunction. For instance, ACE inhibitors, ARBs (Angiotensin II Receptor Blockers), or even other classes of antihypertensives may be options worth exploring.

Additionally, lifestyle modifications can also play a significant role in managing both heart health and erectile function. Regular exercise, a healthy diet, maintaining a healthy weight, and managing stress can all contribute positively to both cardiovascular health and sexual function.

It is also worth noting that if you have underlying conditions such as high cholesterol and hypertension, these can independently contribute to erectile dysfunction. Therefore, a comprehensive approach that includes medication management, lifestyle changes, and possibly counseling for psychological factors may be beneficial.

In summary, while Concan (amlodipine) can be an effective medication for managing blood pressure and coronary artery disease, it may contribute to erectile dysfunction in some patients. It is essential to have an open discussion with your healthcare provider about your symptoms and explore alternative treatment options that may be more suitable for your situation. Your provider can help tailor a treatment plan that addresses both your cardiovascular health and your concerns regarding erectile function.

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