Cholesterol and Liver Enzymes: Risks and Recommendations - Family Medicine

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Cholesterol issues?


Hello Dr.
Hsiao, about a year ago, I had blood tests done at the family medicine department of the hospital and found that my ALT liver enzyme levels were around 40-60, and my cholesterol levels were 217, 207, and 224.
During my last school health check, my liver enzyme level was 37, but my cholesterol was still 219.
I plan to return for a follow-up in November, but I would like to ask if having cholesterol at this level is very dangerous.
Each time, the doctor advises me to exercise more.
I try to avoid greasy foods, but I eat a lot of fruits, and I’m suddenly wondering if consuming too much fruit could be an issue.
I would also like to know different doctors' opinions on what improvements can be made regarding liver enzyme levels and cholesterol.
Thank you!

Cc, 20~29 year old female. Ask Date: 2020/10/23

Dr. Xiao Yongxun reply Family Medicine


Dear Mr.
Cc:
1.
If total cholesterol and low-density lipoprotein (LDL) cholesterol levels are elevated over the long term, the risk of cardiovascular diseases, cerebrovascular diseases, and peripheral artery diseases increases.
Clinical management primarily involves lifestyle modifications, including dietary control, regular physical activity, good weight management, and smoking cessation.
Practically, it is recommended to eat slowly and aim for about 80% fullness at each meal.
It is important to consume a variety of foods without overindulging to maintain a balanced intake of nutrients.
Weekly consumption of egg yolks should ideally be limited to less than two.
Avoid excessive intake of commercially available or convenience store products.
This means reducing the consumption of trans fats (often found in creamers, butter, ghee, three-in-one or two-in-one coffee, milk tea, etc.) and high fructose corn syrup (commonly found in soft drinks, desserts, cola, pastries, etc.).
These types of foods may be harder for the body to metabolize or may be high in calories without providing a sense of fullness, leading to increased blood sugar levels and obesity.
Regular exercise contributes approximately 20-30% to weight and lipid control.
Therefore, moderate exercise and post-meal walks are also very important for weight management.
This can effectively lower cholesterol (CHOLESTEROL) and low-density lipoprotein cholesterol (LDL), thereby reducing the risk of cardiovascular and cerebrovascular diseases.
2.
Hypercholesterolemia or hypertriglyceridemia can lead to fatty liver, resulting in abnormal liver function.
Unless there are specific viral, obstructive, cholestatic, or drug-induced hepatitis conditions, fatty liver-induced liver dysfunction is more common among young individuals.
The solution remains focused on dietary control, regular physical activity, good weight management, and smoking cessation.
3.
I recommend discussing and analyzing the issues thoroughly with your family physician, as this should help you find an ideal solution.

Reply Date: 2020/10/23

More Info


Understanding cholesterol levels and liver enzymes is crucial for maintaining overall health, particularly in preventing conditions such as fatty liver disease and cardiovascular diseases. Your recent blood tests indicate elevated liver enzymes (ALT) and cholesterol levels, which can be concerning but are manageable with lifestyle changes and medical guidance.


Risks Associated with Elevated Cholesterol and Liver Enzymes
1. Cardiovascular Disease: High cholesterol, particularly low-density lipoprotein (LDL) cholesterol, is a significant risk factor for heart disease and stroke. Elevated cholesterol levels can lead to the buildup of plaques in the arteries, which can restrict blood flow and increase the risk of heart attacks.

2. Fatty Liver Disease: Elevated liver enzymes, especially in conjunction with high cholesterol, can indicate fatty liver disease (non-alcoholic fatty liver disease or NAFLD). This condition occurs when excess fat builds up in the liver, potentially leading to inflammation, liver damage, and even cirrhosis if left untreated.

3. Metabolic Syndrome: High cholesterol and liver enzyme levels can be components of metabolic syndrome, a cluster of conditions that increase the risk of heart disease, stroke, and diabetes. This syndrome is often associated with obesity, high blood pressure, and insulin resistance.


Recommendations for Improvement
1. Dietary Adjustments:
- Balanced Diet: Focus on a balanced diet rich in fruits, vegetables, whole grains, and lean proteins. While fruits are healthy, moderation is key. Some fruits are high in sugar, which can contribute to weight gain and increased triglycerides if consumed in excess.

- Limit Saturated Fats: Reduce intake of saturated fats found in red meat and full-fat dairy products, as these can raise cholesterol levels. Instead, opt for healthy fats from sources like avocados, nuts, and olive oil.

- Increase Fiber Intake: Foods high in soluble fiber, such as oats, beans, and lentils, can help lower cholesterol levels. Incorporating these into your meals can be beneficial.

- Avoid Trans Fats: Eliminate trans fats found in many processed foods, as they can significantly raise LDL cholesterol and lower high-density lipoprotein (HDL) cholesterol.

2. Regular Physical Activity:
- Exercise: Regular physical activity can help lower cholesterol levels and improve liver health. Aim for at least 150 minutes of moderate aerobic exercise per week, such as brisk walking, cycling, or swimming. Strength training exercises should also be included at least twice a week.

- Weight Management: If you are overweight, losing even a small percentage of your body weight can help improve liver enzyme levels and cholesterol.

3. Regular Monitoring:
- Follow-Up Appointments: Keep your scheduled appointments with your healthcare provider to monitor liver function and cholesterol levels. Regular blood tests can help track your progress and adjust treatment plans as necessary.

- Medication: If lifestyle changes are insufficient, your doctor may recommend medications to help manage cholesterol levels or liver health. Statins, for example, are commonly prescribed to lower cholesterol and may have beneficial effects on liver enzymes.

4. Limit Alcohol Consumption: Alcohol can exacerbate liver issues, so it’s advisable to limit or avoid alcohol intake, especially if you have elevated liver enzymes.

5. Consult Healthcare Professionals: Since you have concerns about your liver enzymes and cholesterol levels, it’s essential to discuss these with your healthcare provider. They can provide personalized advice based on your health history and current condition.


Conclusion
Elevated cholesterol and liver enzymes can pose significant health risks, but with proactive management through dietary changes, regular exercise, and medical oversight, you can improve your health outcomes. It’s essential to maintain open communication with your healthcare provider and adhere to their recommendations for monitoring and treatment. By making informed lifestyle choices, you can effectively manage your cholesterol levels and support liver health, reducing the risk of serious complications in the future.

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