Concerns About Kidney Health: Managing GERD and eGFR Levels - Urology

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Kidney problems


Hello, doctor.
I currently have issues with gastroesophageal reflux and I'm concerned about the potential impact of medication on my kidneys.
I carefully reviewed my health check-up from May of this year, which showed no abnormalities in urine protein, urine glucose, urine occult blood, kidney ultrasound, blood sugar, or blood pressure.
My blood urea nitrogen was 12.0 mg/dL and creatinine was 0.79 mg/dL, both within normal ranges.
However, my estimated glomerular filtration rate (eGFR) was 92.79 ml/min, which is slightly low.
According to online data, this falls into the category of stage 1 chronic kidney disease.
Since I am only 27 years old, I am quite worried.
Should I visit a hospital for a consultation and medication? Is it safe for me to continue taking medication for my stomach issues? I'm concerned about any potential effects.

Xiang, 20~29 year old female. Ask Date: 2020/10/27

Dr. Du Shixi reply Urology


Hello: The arm function may need further monitoring, as values can fluctuate.
It's important to maintain a healthy lifestyle through proper living, rest, diet, and exercise.
As for whether to continue treatment for gastroesophageal reflux disease (GERD), please have a specialist make the diagnosis first.
Wishing you good health.

Reply Date: 2020/10/27

More Info


It's understandable to have concerns about kidney health, especially when dealing with conditions like gastroesophageal reflux disease (GERD) and fluctuating eGFR levels. Let's break down your situation and address your concerns regarding kidney function, medication safety, and dietary considerations.

Firstly, your eGFR of 92.79 ml/min is indeed within the normal range, although it may be on the lower end. The eGFR is a crucial indicator of kidney function, estimating how well your kidneys filter waste from the blood. An eGFR above 90 ml/min is generally considered normal, while values between 60-89 ml/min may indicate mild kidney dysfunction, particularly in older adults. However, at 27 years old, your eGFR suggests that your kidney function is still quite good, and the slight variation could be attributed to factors such as hydration status, muscle mass, or even laboratory variability.

Regarding your concern about being classified as having Stage 1 chronic kidney disease (CKD), this classification typically requires evidence of kidney damage (like proteinuria) or a consistent eGFR below 90 ml/min over time. Since your urine tests for protein, sugar, and blood are normal, and you have no other signs of kidney damage, it is unlikely that you have CKD at this point. It's essential to monitor your kidney function regularly, especially if you have risk factors such as a family history of kidney disease or other health conditions.

Now, concerning your GERD and the medications you might be taking, it's important to note that many common medications for GERD, such as proton pump inhibitors (PPIs), are generally considered safe for the kidneys when used appropriately. However, long-term use of certain medications can have potential side effects, including kidney-related issues. If you are concerned about the impact of your GERD medications on your kidney health, it would be wise to discuss this with your healthcare provider. They can evaluate your specific situation, consider alternative treatments if necessary, and ensure that your kidney function remains stable.

In terms of dietary management, maintaining a balanced diet is crucial for overall health, including kidney health. Since your kidney function tests are normal, there is no immediate need to restrict your diet significantly. However, it is advisable to limit excessive salt intake, as high sodium can contribute to hypertension and potentially strain the kidneys over time. Focus on a diet rich in fruits, vegetables, whole grains, and lean proteins, which can support both your digestive health and kidney function.

Lastly, if you experience any new symptoms, such as changes in urination, swelling, or persistent fatigue, it would be prudent to seek medical advice. Regular follow-ups with your healthcare provider can help monitor your kidney function and manage your GERD effectively.

In summary, while your eGFR is slightly lower than average, it is still within a normal range for your age, and there are no signs of kidney damage based on your urine tests. Continue to monitor your kidney health, discuss any medication concerns with your doctor, and maintain a healthy diet. If you have further questions or experience any changes in your health, don't hesitate to reach out to your healthcare provider for personalized advice.

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