Thyroid Fine Needle Aspiration: What to Know Before Your Procedure - Internal Medicine

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Thyroid fine-needle aspiration biopsy?


Hello Dr.
Lin,
My mother (70 years old) has been diagnosed with hyperthyroidism and has been advised to undergo a fine needle aspiration biopsy of the thyroid (and neck mass).
The consent form mentions that anticoagulant use is a contraindication for this procedure.
I checked my mother's medication and found that she is taking Lixiana F.C.
Tablets 60mg (edoxaban) (Taiwan FDA registration number 026599).
She often mentions that her heart races and her blood pressure is slightly elevated; after examinations, it was found that she has arrhythmia, which is why her cardiologist prescribed this medication.
The medication instructions state, "Please consult your physician before undergoing invasive procedures or surgery." Since her procedure is scheduled for November 11th and time is tight, and I cannot reach her attending physician, I am seeking advice online.
What should I do now? Thank you for your help!

sara, 40~49 year old female. Ask Date: 2020/11/07

Dr. Lin Jianliang reply Internal Medicine


Generally, a thyroid ultrasound is performed first, followed by a fine needle aspiration biopsy of the thyroid.
It is recommended to inform the physician performing the biopsy beforehand.

Reply Date: 2020/11/07

More Info


Before undergoing a thyroid fine needle aspiration (FNA), especially for a patient like your mother who is on anticoagulant medication such as edoxaban (Lixiana), there are several important considerations to keep in mind.

Understanding Thyroid Fine Needle Aspiration
Thyroid FNA is a minimally invasive procedure used to obtain a sample of thyroid tissue for diagnostic purposes. It is commonly performed to evaluate thyroid nodules or masses, particularly when there is a concern for malignancy. The procedure involves using a thin needle to extract cells from the thyroid gland, which are then examined under a microscope.


Importance of Anticoagulant Management
Anticoagulants, like edoxaban, are prescribed to prevent blood clots, particularly in patients with conditions such as atrial fibrillation or deep vein thrombosis. However, these medications can increase the risk of bleeding during and after invasive procedures. Therefore, it is crucial to manage anticoagulation therapy appropriately before the FNA.


Steps to Take Before the Procedure
1. Contact the Healthcare Provider: Since you mentioned that you cannot reach your mother's primary physician, it is essential to contact the healthcare facility where the procedure will be performed. They may have a protocol in place for managing patients on anticoagulants.

2. Inform the Medical Team: When you arrive for the procedure, ensure that the medical team is aware of your mother's anticoagulant therapy. This information is vital for them to assess the risks and benefits of proceeding with the FNA.

3. Possible Adjustments to Anticoagulation: Depending on the timing of the procedure and the specific anticoagulant, the healthcare provider may recommend temporarily stopping edoxaban. This decision will depend on factors such as the indication for anticoagulation, your mother's overall health, and the risk of thromboembolic events if the medication is paused.

4. Timing Considerations: If edoxaban needs to be held, the healthcare provider will give specific instructions on when to stop the medication before the procedure and when to resume it afterward. Typically, for medications like edoxaban, it may be recommended to hold the medication for at least 24-48 hours before the procedure, but this can vary based on individual circumstances.

5. Monitoring and Follow-Up: After the FNA, your mother will need to be monitored for any signs of bleeding or complications. The healthcare provider will also discuss when it is safe to resume anticoagulation therapy.


Additional Considerations
- Pre-Procedure Assessment: Ensure that your mother undergoes a thorough pre-procedure assessment, including a review of her medical history, current medications, and any recent lab work that may be relevant.


- Discussing Symptoms: Since your mother has reported symptoms such as rapid heart rate and high blood pressure, it may be beneficial to discuss these with the healthcare provider as well. They may need to consider her cardiovascular status when planning the procedure.

- Patient Education: Educate your mother about what to expect during and after the FNA. This includes potential side effects, such as mild discomfort or bruising at the needle site, and the importance of reporting any unusual symptoms.


Conclusion
In summary, managing anticoagulation therapy is critical before a thyroid fine needle aspiration, particularly for patients on medications like edoxaban. It is essential to communicate with the healthcare team to ensure that your mother’s safety is prioritized. If you are unable to reach her primary physician, consider contacting the facility where the procedure will take place for guidance. Proper planning and communication will help mitigate risks and ensure a successful outcome for the procedure.

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