Managing Menstrual Irregularities with Norethindrone: A Patient's Journey - Obstetrics and Gynecology

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Using progesterone norethindrone to induce menstruation?


To avoid the wedding dates of October 17 and November 14, I started taking medication on September 23 (the fifth day of my menstrual cycle) and continued until October 16.
However, I experienced menstruation that included both brown and bright red blood for about three days.
Since I was running out of medication, I quickly called my original gynecology clinic to ask for advice.
They instructed me to finish the medication and then return for a follow-up appointment.
During the follow-up, because I was concerned about the upcoming wedding on November 14, I requested another month of progesterone and continued taking it until November 7.
My menstruation returned, similar to before, with brown and bright red blood.
Since it had started, I decided to stop the medication on my own.
It lasted for two days and then stopped.
As of today, November 20, I still have not had my period, and I am preparing for conception.
Should I go back to the gynecologist for a check-up, or should I wait and see if my period returns? Thank you.

Ru, 20~29 year old female. Ask Date: 2020/11/20

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, my period started on November 7th, so my next period should be around December 8th.
To conceive, just let nature take its course.
Wishing you good health!

Reply Date: 2020/11/20

More Info


Managing menstrual irregularities can be a complex issue, especially when hormonal medications like Norethindrone are involved. Norethindrone is a synthetic progestin commonly used to treat various menstrual disorders, including irregular periods, heavy bleeding, and to help regulate the menstrual cycle. It works by mimicking the effects of natural progesterone, which can help stabilize the endometrial lining and prevent excessive bleeding.

In your case, it seems that you started taking Norethindrone on September 23rd, aiming to manage your menstrual cycle around your wedding dates. You experienced some irregular bleeding, which is not uncommon when starting hormonal treatments. The presence of both brown (old blood) and bright red blood can indicate a mix of old and new menstrual flow, often seen during the adjustment period to hormonal medications.

It's important to follow your healthcare provider's advice regarding medication adherence. Since your doctor advised you to complete the course of medication, it's generally best to do so unless you experience severe side effects or have specific concerns. After stopping the medication, it's not unusual for your menstrual cycle to take some time to return to its regular rhythm, especially after a period of hormonal manipulation.

Given that you stopped taking the medication and have not had a period since November 7th, it would be prudent to monitor your body for a little longer. However, if you are planning to conceive, it is essential to have a clear understanding of your menstrual cycle and ovulation patterns. Irregular cycles can make it more challenging to predict ovulation, which is crucial for conception.

Here are some considerations for your situation:
1. Timing of Your Cycle: After stopping hormonal treatments, it can take a few cycles for your body to readjust and for your menstrual cycle to normalize. Some women may experience delays in their periods, while others may have irregular cycles for a few months.

2. Pregnancy Considerations: If you are actively trying to conceive, it is advisable to consult with your gynecologist. They can provide guidance on tracking ovulation and understanding your fertile window. If your period does not return in the next few weeks, a pregnancy test may be warranted, especially if you have had unprotected intercourse.

3. Follow-Up Appointment: If you have concerns about your menstrual irregularities or if your period does not return within a reasonable timeframe (typically a few months), it is wise to schedule a follow-up appointment with your gynecologist. They can assess your situation, possibly perform tests to rule out any underlying issues, and discuss alternative treatments if necessary.

4. Lifestyle Factors: Stress, significant weight changes, and other lifestyle factors can also affect your menstrual cycle. Ensure you are maintaining a healthy lifestyle, including a balanced diet and regular exercise, which can positively influence your menstrual health.

5. Communication with Your Doctor: When you do see your doctor, be prepared to discuss your menstrual history, any symptoms you have experienced, and your plans for conception. This information will help them provide you with the best care tailored to your needs.

In summary, while it may be tempting to wait and see if your period returns, given your plans for pregnancy, it would be beneficial to consult with your gynecologist sooner rather than later. They can help you navigate this transition and ensure that you are on the right path toward achieving your reproductive goals.

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