The glomerular filtration rate (GFR) has been continuously declining?
I would like to inquire about my health check report.
My glomerular filtration rate (GFR) is 78, creatinine is 1.09, blood urea nitrogen (BUN) is 13.2, and uric acid is 4.9.
All other reports are normal, and there is no presence of protein in the urine test.
Given my age, the GFR seems somewhat low.
I have been having blood tests every six months, and it decreased from 87 last year to 78 this year.
Should I schedule an appointment with a nephrologist for further evaluation? Thank you.
Liao, 30~39 year old female. Ask Date: 2020/12/10
Dr. Wu Hongjie reply Internal Medicine
Hello: The glomerular filtration rate (GFR) is a variable value.
If the GFR is <60 ml/min and persists for more than three months, the likelihood of a diagnosis of renal failure is high.
If the GFR is >60 and there are no other pathological findings (such as renal biopsy), structural abnormalities, or proteinuria, then the next follow-up may return to normal (baseline) values.
It is recommended to start with lifestyle changes: weight loss, a low-protein diet, increased water intake, and controlling blood pressure and blood sugar levels.
The night before the next examination, it is advisable to drink more water and avoid (or limit) meat consumption.
Testing the following day will yield more accurate results.
Reply Date: 2020/12/10
More Info
When evaluating kidney function, the estimated glomerular filtration rate (eGFR) is a crucial metric. In your case, an eGFR of 78 mL/min indicates that your kidney function is still within the normal range, albeit on the lower end. The normal eGFR range is typically considered to be above 90 mL/min, but values can vary based on age, sex, and muscle mass. It's important to note that eGFR can fluctuate due to various factors, including hydration status, dietary intake, and acute illnesses.
Your serum creatinine level of 1.09 mg/dL is also within the normal range for most adults, although it is slightly elevated compared to the ideal values for younger individuals. The blood urea nitrogen (BUN) level of 13.2 mg/dL and uric acid level of 4.9 mg/dL are both within normal limits, which is reassuring. Additionally, the absence of protein in your urine is a positive sign, as persistent proteinuria can indicate kidney damage.
Given that your eGFR has declined from 87 to 78 over the past year, it is understandable to be concerned. A decline in kidney function can be indicative of underlying issues, such as hypertension, diabetes, or other renal pathologies. However, a single drop in eGFR does not necessarily mean that you have chronic kidney disease (CKD). CKD is typically diagnosed when there is a consistent decline in kidney function over time, along with other indicators such as persistent proteinuria or structural abnormalities.
In your case, since you are already monitoring your kidney function every six months, it would be prudent to continue this practice. However, considering the decline in eGFR, it may be beneficial to consult a nephrologist for a more comprehensive evaluation. A nephrologist can perform additional tests to assess your kidney function more thoroughly, including imaging studies or a more detailed analysis of your urine. They can also help identify any potential risk factors that may be contributing to the decline in your eGFR.
When to see a nephrologist can vary, but generally, it is advisable to seek their expertise if:
1. Your eGFR falls below 60 mL/min, which indicates a more significant decline in kidney function.
2. You have persistent proteinuria or hematuria (blood in urine).
3. You have a family history of kidney disease or other risk factors such as diabetes or hypertension that are not well-controlled.
4. You experience symptoms such as swelling, fatigue, or changes in urination patterns.
In summary, while your current eGFR of 78 does not immediately necessitate a visit to a nephrologist, the recent decline and your age warrant a proactive approach. Consulting with a specialist can provide peace of mind and ensure that any potential issues are addressed early on. Additionally, maintaining a healthy lifestyle, including a balanced diet, regular exercise, and proper management of any existing health conditions, can help support your kidney health.
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