the Loss of Nail Matrix: Causes and Solutions - Dermatology

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The absence of squamous epithelium?


Hello doctor, I noticed the sudden disappearance of my nail matrix two days ago, which has caused my proximal nail fold to be movable.
The entire nail plate and proximal nail fold appear slightly elevated.
Is this phenomenon related to any health issues? How can I encourage the regrowth of the nail matrix to secure it again? Thank you.

Hank, 10~19 year old female. Ask Date: 2020/12/10

Dr. Wu Yuxin reply Dermatology


There may be an injury or infection that requires medical treatment.

Reply Date: 2020/12/10

More Info


The loss of the nail matrix, which is the tissue under the base of the nail that produces new nail cells, can lead to significant changes in the appearance and health of your nails. When the nail matrix is damaged or absent, it can result in various nail abnormalities, including the detachment of the nail plate, changes in nail shape, and even the inability to grow a healthy nail.


Causes of Nail Matrix Loss
1. Trauma: Physical injury to the nail can damage the nail matrix. This could be due to stubbing your toe, slamming your finger in a door, or any other form of blunt force trauma.

2. Infections: Fungal infections, bacterial infections, or viral infections can affect the nail matrix. Conditions like onychomycosis (fungal nail infection) can lead to nail discoloration, thickening, and eventual loss.

3. Dermatological Conditions: Skin diseases such as psoriasis or eczema can also impact the nail matrix. Psoriasis, in particular, is known to cause pitting, ridges, and even nail loss.

4. Systemic Diseases: Certain systemic conditions, such as thyroid disorders, autoimmune diseases, or nutritional deficiencies (like biotin deficiency), can affect nail health and growth.

5. Chemotherapy or Medications: Some medications, especially those used in chemotherapy, can lead to changes in nail growth and structure.

6. Genetic Factors: Some individuals may have a genetic predisposition to nail abnormalities, which can include issues with the nail matrix.


Implications for Health
The loss of the nail matrix can have several implications for your health. While it may not pose an immediate threat, it can indicate underlying health issues that may need to be addressed. Additionally, the appearance of your nails can be a reflection of your overall health. Changes in nail structure can sometimes signal nutritional deficiencies or systemic diseases.


Solutions and Management
1. Consult a Dermatologist: The first step is to consult a dermatologist or a healthcare professional who specializes in nail disorders. They can assess the condition of your nails and determine the underlying cause of the matrix loss.

2. Protect the Nail Area: If the nail matrix is exposed, it's important to protect it from further injury or infection. Keeping the area clean and covered can help prevent complications.

3. Nutritional Support: Ensure that you are getting adequate nutrition, particularly vitamins and minerals that support nail health, such as biotin, zinc, and protein. A balanced diet can promote healthy nail growth.

4. Topical Treatments: Depending on the cause, topical treatments may be recommended. For instance, antifungal creams can be used if a fungal infection is present.

5. Avoid Trauma: Be cautious to avoid further trauma to the nail area. Wearing protective gloves during activities that may cause injury can help.

6. Patience and Time: Nails grow slowly, and it may take time for the nail matrix to heal and for a new nail to grow. Regular follow-ups with your healthcare provider can help monitor progress.

7. Surgical Options: In severe cases where the nail matrix is permanently damaged, surgical options may be considered to reconstruct the nail bed or matrix.

In conclusion, the loss of the nail matrix can be concerning, but with appropriate care and management, it is possible to promote healthy nail regrowth. It is essential to address any underlying health issues and to follow up with a healthcare professional for tailored advice and treatment options.

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