Frequent Muscle Twitches: When to Worry About ALS - Neurology

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Involuntary muscle twitching?


Hello doctor, recently I've been experiencing occasional muscle twitching in both of my legs, and it's quite frequent.
I would like to ask if benign twitching can occur this often? I'm worried it might be related to ALS.

Fan, 10~19 year old female. Ask Date: 2020/12/16

Dr. Jiang Junyi reply Neurology


Hello: The condition you are concerned about, commonly known as amyotrophic lateral sclerosis (ALS), primarily involves issues with motor neurons.
Motor neurons control muscle movement; generally, the motor neurons in the brain are referred to as upper motor neurons, while those in the brainstem and spinal cord are called lower motor neurons.
When motor neurons become damaged, our muscles do not receive adequate nutrients and chemicals, which can lead to muscle death.
This is a chronic muscle-wasting disease that may result in muscle atrophy.
If upper motor neurons die, abnormal signal transmission may cause muscle twitching.
However, clinical diagnosis requires methods such as electromyography (EMG) and muscle biopsy.
Neurologists specializing in neuromuscular diseases are more familiar with these types of conditions, and I recommend consulting such a specialist.
Wishing you good health, peace, and joy.
Dr.
Jiang from Taoyuan Medical Center cares about you.

Reply Date: 2020/12/16

More Info


Frequent muscle twitches, also known as fasciculations, can be concerning, especially when one is worried about serious conditions like Amyotrophic Lateral Sclerosis (ALS). However, it's important to understand that muscle twitches are common and can occur for a variety of benign reasons.
Firstly, benign muscle twitches can be caused by several factors, including stress, anxiety, fatigue, dehydration, or electrolyte imbalances. These twitches are often harmless and may not indicate any underlying neurological condition. In many cases, they can be exacerbated by lifestyle factors such as excessive caffeine intake, lack of sleep, or overexertion during physical activities.
In the context of ALS, it’s crucial to note that while muscle twitching can be a symptom, it is not definitive on its own. ALS is characterized by the degeneration of motor neurons, which leads to muscle weakness, atrophy, and eventually paralysis. The presence of muscle twitches in ALS is typically accompanied by other symptoms, such as muscle weakness, difficulty speaking or swallowing, and significant muscle wasting. If you are experiencing muscle twitches without any accompanying weakness or atrophy, it is less likely to be related to ALS.

Regarding the frequency of the twitches, benign fasciculations can indeed occur frequently, sometimes multiple times a day, without indicating a serious condition. If the twitches are isolated to certain muscles and do not lead to weakness or functional impairment, they are generally not a cause for concern.
However, if you notice additional symptoms such as persistent weakness, changes in coordination, or difficulty with speech or swallowing, it would be prudent to seek a medical evaluation. A neurologist can perform a thorough examination, which may include electromyography (EMG) and nerve conduction studies, to assess the health of your motor neurons and rule out conditions like ALS.

In summary, while frequent muscle twitches can be alarming, they are often benign and not indicative of ALS, especially if there are no accompanying symptoms of weakness or atrophy. It is always best to consult with a healthcare professional if you have concerns about your symptoms, as they can provide personalized advice and reassurance based on a comprehensive evaluation of your health. Remember, anxiety about health can sometimes amplify symptoms, so addressing both physical and mental well-being is essential.

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