The effects of psychiatric medications on elevated intraocular pressure/glaucoma?
I have a sensitive constitution and experience side effects from psychiatric medications much more noticeably than the average person.
Some medications cause me to miss my period, others make me tremble to the point of being unable to walk, some lead to lactation, others cause extrapyramidal symptoms, and some nearly required a blood transfusion.
I also have abnormal liver function.
Currently, I am taking the following medications: Rivotril 2mg at bedtime, Propranolol 10mg twice daily (morning and evening), Mezapin 25mg (1.5 tablets at bedtime), Lamictal 50mg (2 tablets in the evening and 2 at bedtime), and Abilify 15mg at bedtime.
As of November 5th, I have been diagnosed with early-stage glaucoma, but the eye pressure remains at 20-21 despite using pressure-lowering eye drops.
I would like to know if psychiatric medications can lead to increased eye pressure and subsequently glaucoma, or if there are specific classes of psychiatric medications I should avoid.
Is there a causal relationship between psychiatric medications and glaucoma? Thank you.
Ke bu ke yi, 30~39 year old female. Ask Date: 2020/12/29
Dr. Liao Dinglie reply Psychiatry
Hello,
Regarding the pharmacological treatment of mental disorders, it seems that you experience more side effects than the average person.
This condition must be quite challenging for you.
While medication may provide some benefits, the side effects can limit your options and may require lower dosages.
You mentioned that you currently have glaucoma.
It is advisable to discuss your glaucoma treatment options with your ophthalmologist during your regular follow-ups.
Certain medications that can affect glaucoma may have anticholinergic effects, which can lead to symptoms such as dry mouth and constipation.
Your medication regimen is not necessarily more intense compared to other patients.
If adjustments are needed for the medication combination you mentioned, please consult both your ophthalmologist and psychiatrist.
Wishing you good mental and physical health.
Dr.
Liao Ding-Lie
Reply Date: 2020/12/29
More Info
The relationship between psychiatric medications and eye pressure, particularly in the context of glaucoma, is a complex and important topic. Based on the information provided, it is clear that you have a heightened sensitivity to medication side effects, which can complicate your treatment regimen.
Firstly, it is essential to understand that certain psychiatric medications can indeed have an impact on eye pressure. For instance, some antidepressants, antipsychotics, and mood stabilizers have been associated with changes in intraocular pressure (IOP). However, the extent of this impact can vary significantly among individuals, as you have experienced with your sensitivity to side effects.
1. Psychiatric Medications and Eye Pressure:
Medications such as Propranolol (a beta-blocker) are generally not known to increase eye pressure; in fact, they are sometimes used to treat conditions like glaucoma. However, other medications, particularly certain antipsychotics and antidepressants, may have side effects that could potentially lead to increased IOP. For example, some studies have suggested that medications like Olanzapine and Risperidone can lead to elevated eye pressure in susceptible individuals.
In your case, you are currently taking Abilify (Aripiprazole), which is an atypical antipsychotic. While it is not commonly associated with increased IOP, individual responses can vary. It is crucial to monitor your eye pressure regularly, especially since you have been diagnosed with early-stage glaucoma.
2. Glaucoma and Medication Management:
Given your diagnosis of early-stage glaucoma and the fact that your eye pressure remains elevated (20-21 mmHg), it is important to work closely with both your psychiatrist and ophthalmologist. They can help you evaluate the risk-benefit ratio of your current medications. If any of your psychiatric medications are suspected to contribute to increased eye pressure, your healthcare providers may consider alternative treatments that have a more favorable profile regarding eye health.
3. Monitoring and Adjustments:
Regular eye exams and pressure checks are essential for managing glaucoma. Since you are already experiencing elevated IOP, it is advisable to adhere to the treatment plan prescribed by your ophthalmologist, which may include topical medications to lower eye pressure. Additionally, if you notice any changes in your vision or experience discomfort, it is crucial to report these symptoms to your healthcare provider immediately.
4. Lifestyle and Other Considerations:
In addition to medication management, lifestyle factors can also influence eye pressure. Stress and anxiety can lead to temporary increases in IOP, so managing these conditions through therapy, mindfulness, or relaxation techniques may be beneficial.
5. Conclusion:
In summary, while there is no definitive causal relationship established between psychiatric medications and glaucoma, certain medications can influence eye pressure, and individual responses can vary widely. Given your sensitivity to medications and your current diagnosis, it is vital to maintain open communication with your healthcare providers. They can help tailor your treatment plan to minimize risks while effectively managing your psychiatric symptoms. Regular monitoring of your eye health will be crucial in preventing the progression of glaucoma and ensuring your overall well-being.
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