Do Antibiotics Like Clindamycin Affect Birth Control Pills? - Obstetrics and Gynecology

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Antibiotics and contraceptives?


Excuse me, doctor.
I would like to ask, I have been taking Diane for 2 months, and recently I caught a cold and took clindamycin antibiotic for 3 days.
I checked online and it seems that there are no typical interactions with antibiotics.
I am wondering if clindamycin will affect the contraceptive effectiveness?

Niming, 20~29 year old female. Ask Date: 2021/01/03

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, it generally does not have an impact.
Wishing you good health.

Reply Date: 2021/01/03

More Info


When it comes to the interaction between antibiotics like Clindamycin and birth control pills, it's important to understand how these medications work and their potential effects on hormonal contraceptives. Clindamycin is a lincosamide antibiotic that is primarily used to treat bacterial infections. It is not known to have a significant impact on the effectiveness of hormonal contraceptives, including birth control pills like Diane (Diane-35).

Most antibiotics do not interfere with the effectiveness of birth control pills. The primary concern arises with a specific class of antibiotics known as rifampin and its derivatives, which are known to induce liver enzymes that can decrease the effectiveness of hormonal contraceptives. However, Clindamycin does not belong to this category and is not associated with such interactions.

The concern about antibiotics affecting birth control pills often stems from the potential for gastrointestinal side effects, such as vomiting or diarrhea, which can reduce the absorption of the contraceptive pill if they occur shortly after taking it. If you experience severe gastrointestinal symptoms while on antibiotics, it is advisable to use a backup contraceptive method, such as condoms, during that time.

In your case, since you have been taking Diane for two months and have recently taken Clindamycin for a short duration (three days), there is no evidence to suggest that this antibiotic will compromise the effectiveness of your birth control pill. However, if you have any concerns or experience any unusual symptoms, it is always best to consult with your healthcare provider for personalized advice.

Additionally, it is important to consider that while antibiotics like Clindamycin are effective in treating infections, they should be used judiciously, especially in the context of long-term use. Overuse of antibiotics can lead to antibiotic resistance, which is a growing public health concern. Therefore, it is essential to follow your healthcare provider's recommendations regarding the use of antibiotics and to discuss any concerns you may have about their use in conjunction with other medications, including birth control.

In summary, Clindamycin is not expected to affect the efficacy of your birth control pills. However, if you have any doubts or experience any adverse effects, do not hesitate to reach out to your healthcare provider for further guidance. They can provide you with the most accurate information based on your specific health situation and medication regimen.

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Hello, it generally does not have an impact. Wishing you good health.

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