Heart Rate Changes and Medication Effects in Cardiovascular Health - Cardiology

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Medication issues


Hello, Doctor.
I have been taking 5 mg of Concor (Bisoprolol), and I am not sure if it is related to the medication, but my resting heart rate is around the 50s, and while sleeping, it drops to the 40s.
Is this normal? Additionally, last night while I was sleeping, I felt like my heart skipped a beat, and when I woke up in the morning, my legs were shaking quite a bit.
Can you explain what might be happening? Sometimes, I also feel certain muscles in my body twitching continuously.
Thank you for your help.
🙏

Niming, 20~29 year old female. Ask Date: 2021/01/10

Dr. He Dongjin reply Cardiology


Hello, taking Kankena, my resting heart rate is 50, and it drops to 40 while sleeping.
Is this normal? Kankena is used to treat irregular heartbeats and palpitations.
In the morning, my legs tremble, and my muscles keep twitching.
Occasionally, my body feels unusual, but it may not necessarily be caused by the heart.
I pray for your peace and well-being.
Changhua Hospital cares about you.

Reply Date: 2021/01/10

More Info


When it comes to understanding heart rate changes and the potential effects of medications on cardiovascular health, it is essential to consider several factors, including the specific medications being taken, the individual's overall health status, and any accompanying symptoms.

In your case, you mentioned taking a medication called "康肯" (Kankin), which is likely a beta-blocker or a similar type of drug. These medications are commonly prescribed for various cardiovascular conditions, including hypertension and arrhythmias. One of the known effects of beta-blockers is a reduction in heart rate. It is not uncommon for patients on these medications to experience a resting heart rate in the range of 50 beats per minute (bpm) or even lower, especially during sleep. A resting heart rate below 60 bpm is termed bradycardia, and while it can be normal for some individuals, particularly athletes or those on beta-blockers, it can also indicate an underlying issue if accompanied by symptoms.

You reported experiencing a heart rate that drops to the 40s during sleep and occasional sensations of "missed beats" or palpitations. These sensations can be concerning, especially if they are new or accompanied by other symptoms such as dizziness, shortness of breath, or fatigue. The feeling of a skipped heartbeat, known as a palpitation, can be caused by various factors, including anxiety, caffeine intake, electrolyte imbalances, or the effects of medications. In your case, since you are on medication, it is crucial to consider whether the dosage or type of medication may need adjustment.

The trembling in your legs upon waking could be related to several factors, including anxiety, muscle fatigue, or even a side effect of the medication. If you are experiencing muscle twitching or spasms in various parts of your body, this could also be linked to electrolyte imbalances, dehydration, or medication side effects. It is essential to maintain adequate hydration and ensure that your diet includes sufficient electrolytes, such as potassium and magnesium, which are vital for muscle function and heart health.

Given your symptoms and the changes in your heart rate, it is advisable to consult with your healthcare provider. They may recommend monitoring your heart rate more closely, possibly through a Holter monitor, which records heart activity over 24 hours. This can help determine if the bradycardia is significant and whether any arrhythmias are present. Additionally, your doctor may want to review your current medications to assess if adjustments are necessary, especially if you are experiencing side effects that impact your quality of life.

In summary, while a lower heart rate can be normal for some individuals, especially those on beta-blockers, it is essential to monitor for any concerning symptoms. The sensations of missed beats and muscle twitching warrant further evaluation. Maintaining open communication with your healthcare provider is crucial to ensure that your cardiovascular health is managed effectively and safely. Regular follow-ups and possibly adjusting your medication regimen may be necessary to optimize your heart health and overall well-being.

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