Do Cold Medications Interact with Birth Control Pills? - Obstetrics and Gynecology

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Drug interactions between cold medications and contraceptives?


Hello Doctor, I have been taking the birth control pill, Meisi Nong, for over a year.
Recently, I caught a cold and initially bought Chang'an's cold capsules, which contain Acetaminophen 300mg, Potassium Guaiacol Sulfonate 60mg, Chlorpheniramine Maleate 2.5mg, Dextromethorphan Hydrobromide 15mg, DL-Methylephedrine Hydrobromide 10mg, Caffeine Anhydrous 30mg, Thiamine Hydrochloride 8mg, and Riboflavin 4mg.
Later, I also consulted a doctor who prescribed me cold medication containing COMPOUND GLYCYRRHIZIN 20mg, TINTENSALINE S.C.
TABLETS, Serenal (FOAN), EGOLDER TABLETS 60mg, and LEVOZINE F.C.
TABLETS.
I would like to know if any of these medications could interact with the birth control pill and reduce its effectiveness.
Thank you, Doctor!

Lori, 20~29 year old female. Ask Date: 2021/02/16

Dr. Zhang Kunmin reply Obstetrics and Gynecology


Hello, the following medications may interact with oral contraceptives: 1.
Antibiotics (Penicillin, Cephalosporins, Erythromycin, Sulfonamides, Bactrim, Chloramphenicol) - may reduce the gut flora that aids in absorption, thereby decreasing the effectiveness of contraceptives.
2.
Sedatives (Barbiturates) - increase the metabolism of contraceptives, reducing their effectiveness.
3.
Antiepileptic drugs (Primidone, Phenytoin, Carbamazepine) - increase the metabolism of contraceptives, reducing their effectiveness.
4.
Tuberculosis medications (Rifampicin, Isoniazid).
5.
Antidiabetic medications (Rosiglitazone).
6.
Acetaminophen and Ascorbic acid (Vitamin C) - may inhibit estrogen metabolism, leading to increased concentrations and a higher incidence of side effects.
7.
Oral contraceptives can affect the action of anticoagulants.
8.
Smoking - increases the metabolism of contraceptives, reducing their effectiveness.
It is suggested that if necessary, you consult a physician for evaluation.
Thank you! Wishing you safety and health.
Dr.
Zhang

Reply Date: 2021/02/16

More Info


When it comes to the interaction between cold medications and birth control pills, it's important to understand how various components of these medications can affect hormonal contraceptives. Generally, most over-the-counter cold medications, including those containing acetaminophen, dextromethorphan, and antihistamines like chlorpheniramine, do not significantly impact the effectiveness of birth control pills. However, there are some nuances to consider.


Cold Medications and Birth Control Pills
1. Common Ingredients: The cold medications you mentioned contain a variety of ingredients. Acetaminophen is a pain reliever and fever reducer that does not interfere with hormonal contraceptives. Dextromethorphan is a cough suppressant, and potassium guaiacol sulfonate is an expectorant, both of which also do not affect birth control efficacy. Chlorpheniramine is an antihistamine, and while it can cause drowsiness, it does not interact with birth control pills.

2. Prescription Medications: The prescription medications you received, such as Glycyrrhizin and Levozine, are also not known to interfere with the effectiveness of birth control pills. Glycyrrhizin is derived from licorice root and is often used for its anti-inflammatory properties, while Levozine (levocetirizine) is an antihistamine. Neither of these has been shown to reduce the effectiveness of hormonal contraceptives.

3. Antibiotics and Other Medications: The primary concern regarding birth control effectiveness typically arises with certain antibiotics, particularly rifampin and rifabutin, which can decrease the effectiveness of hormonal contraceptives. However, most common antibiotics do not have this effect. Additionally, some medications used for seizures or HIV treatment can also interact with birth control pills.

4. Hormonal Fluctuations: While cold medications themselves may not directly affect birth control efficacy, it's worth noting that illness can sometimes lead to changes in hormone levels or metabolism. Stress, fever, or significant changes in health can potentially affect how your body processes hormones, but this is generally not a concern with short-term use of cold medications.

5. Consulting Healthcare Providers: If you have concerns about specific medications and their interactions with your birth control, it’s always best to consult with your healthcare provider or pharmacist. They can provide personalized advice based on your health history and the specific medications you are taking.


Conclusion
In summary, the cold medications you mentioned, both over-the-counter and prescription, are not known to significantly interact with birth control pills and should not reduce their effectiveness. However, if you experience any unusual symptoms or have further concerns, it's advisable to reach out to your healthcare provider for guidance. Maintaining open communication with your healthcare team is crucial for managing your health effectively, especially when dealing with multiple medications.

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