Posterior Longitudinal Ligament Calcification and Its Management - Neurosurgery

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Regarding posterior longitudinal ligament calcification?


Hello Director Lai, I have a problem with calcification of the posterior longitudinal ligament, which has already caused discomfort in my neck.
I heard that this is a condition unique to Asians.
May I ask, Director Lai, is the calcification of the posterior longitudinal ligament caused by excessive calcium in the body? Should I reduce my calcium intake, such as drinking less milk or consuming foods high in calcium like sesame? What measures can I take to prevent further calcification of the posterior longitudinal ligament? Thank you, Director.

Lin Jie Shen, 40~49 year old female. Ask Date: 2021/02/22

Dr. Lai Zhaokang reply Neurosurgery


Hello: According to the literature: 1.
Ossification of the posterior longitudinal ligament (OPLL) is associated with various congenital genetic factors and multiple influencing factors.
2.
Individuals who prefer pickled foods, such as kimchi, and staple foods like rice have a significantly higher risk of developing OPLL compared to those who tend to consume chicken and soy products.
3.
The proportion of patients with a history of diabetes is notably high.
4.
Various hormonal imbalances lead to disturbances in bone formation and resorption, disrupting the balance of osteogenesis and bone resorption, which induces ectopic ossification of the posterior longitudinal ligament.
5.
OPLL is more common in Asia, particularly Japan, and is the primary cause of cervical spondylotic myelopathy, with a male incidence rate three times that of females.
6.
It may be due to long-term cervical strain accelerating degeneration, causing subperiosteal hemorrhage to infiltrate the posterior longitudinal ligament, gradually leading to calcification or ossification, thus forming OPLL.
Therefore, my recommendations are: 1.
Congenital genetic factors, ethnicity, and gender cannot be changed.
2.
Dietary factors, such as pickled foods and those that induce hyperglycemia, should be moderately reduced.
3.
Avoid excessive cervical strain; limit time spent looking down and engage in moderate neck and shoulder exercises.
4.
According to the literature, there is no significant correlation with calcium intake; however, moderate supplementation is still recommended.
Best wishes to you.
// Dr.
Chao-Kang Lai, Chief of Spine Neurosurgery.

Reply Date: 2021/02/22

More Info


Posterior Longitudinal Ligament Calcification (PLLC) is a condition characterized by the calcification or ossification of the posterior longitudinal ligament, which runs along the spine and helps stabilize it. This condition is indeed more prevalent in certain populations, particularly in East Asian individuals, and can lead to various symptoms, including neck pain, stiffness, and in severe cases, neurological deficits due to spinal cord compression.

The exact etiology of PLLC is not fully understood, but it is believed to be multifactorial. While some studies suggest that genetic predisposition plays a significant role, environmental factors, mechanical stress on the spine, and nutritional aspects may also contribute. It is important to note that PLLC is not directly caused by excessive calcium intake. Instead, it is associated with a complex interplay of factors, including age, genetic factors, and possibly chronic inflammation or degeneration of the spinal structures.

Regarding dietary calcium intake, it is essential to maintain a balanced diet. Calcium is crucial for bone health, and reducing calcium intake drastically is not typically recommended unless advised by a healthcare professional. Instead of eliminating calcium-rich foods like milk and sesame, it may be more beneficial to focus on overall dietary balance and lifestyle modifications.
To manage and potentially prevent the progression of PLLC, consider the following strategies:
1. Physical Therapy: Engaging in physical therapy can help strengthen the muscles around the neck and spine, improve flexibility, and reduce pain. A physical therapist can design a tailored exercise program that focuses on stretching and strengthening the neck and upper back muscles.

2. Posture Correction: Maintaining good posture is crucial in preventing further stress on the cervical spine. Ergonomic adjustments at your workstation, especially if you spend long hours sitting, can help alleviate strain on the neck.

3. Weight Management: Maintaining a healthy weight can reduce the mechanical load on the spine. Regular exercise and a balanced diet can help achieve and maintain a healthy weight.

4. Regular Monitoring: Regular follow-ups with your healthcare provider are essential to monitor the progression of PLLC. Imaging studies may be necessary to assess changes in the condition over time.

5. Pain Management: If you experience significant discomfort, discuss pain management options with your healthcare provider. This may include medications, injections, or alternative therapies such as acupuncture.

6. Nutritional Considerations: While it is not necessary to reduce calcium intake drastically, ensuring adequate intake of other nutrients that support bone health, such as vitamin D and magnesium, is important. These nutrients work synergistically with calcium to maintain bone density and overall health.

7. Avoiding High-Impact Activities: If you have been diagnosed with PLLC, it may be wise to avoid high-impact sports or activities that could exacerbate your symptoms or lead to further injury.

In conclusion, while PLLC is a condition that can lead to discomfort and other complications, it is not solely caused by high calcium intake. Instead, a holistic approach that includes physical therapy, posture correction, weight management, and regular monitoring can help manage symptoms and potentially slow the progression of the condition. Always consult with your healthcare provider before making significant changes to your diet or exercise routine to ensure they are appropriate for your specific situation.

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