Persistent Low Blood Pressure in Dialysis Patients - Cardiology

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Persistent hypotension


Hello, Doctor.
My father is a dialysis patient and had a drug-eluting stent placed in his heart a year ago.
He regularly takes one tablet of Kankin, one tablet of Berkey, and one tablet of Farmatran enteric-coated tablets.
Over the past three months, his blood pressure has been around 80s/50s, and his heart rate sometimes measures over 60 and sometimes over 120.
On March 2, during a follow-up visit to the cardiology department, the doctor performed an electrocardiogram and found issues with arrhythmia.
He prescribed "Zardel" one tablet in the morning and one in the evening, and replaced Berkey with half a tablet of Clopidogrel.
The doctor previously thought that the low blood pressure might be due to dehydration.
Recently, his dry weight has increased by nearly 1.5 kilograms, but he is still experiencing low blood pressure.
Could this be caused by the arrhythmia? Does dialysis also lead to persistent low blood pressure? Should I ask the doctor for medication to raise his blood pressure during the follow-up visit next week?

Awei, 30~39 year old female. Ask Date: 2021/03/05

Dr. Wu Xueming reply Cardiology


If adjusting dry body weight and dehydration levels still results in low blood pressure, a nephrologist can prescribe oral vasopressors.

Reply Date: 2021/03/05

More Info


Understanding persistent low blood pressure in dialysis patients is a multifaceted issue that requires careful consideration of various factors, including the patient's overall health, medication regimen, and the specifics of their dialysis treatment. In your father's case, it appears that he has a complex medical history, including a heart condition that necessitated the placement of a drug-eluting stent, and he is currently undergoing dialysis.
Low blood pressure (hypotension) in dialysis patients can be attributed to several factors. One of the most common causes is fluid removal during dialysis. If too much fluid is removed too quickly, it can lead to a decrease in blood volume, resulting in low blood pressure. This is particularly relevant for patients who have undergone long-term dialysis, as they may have a lower tolerance for fluid shifts. Adjusting the "dry weight" (the target weight after dialysis) is crucial; if your father's dry weight has been increased by 1.5 kg and he is still experiencing low blood pressure, it may indicate that further adjustments are necessary.

Additionally, the medications your father is taking can also contribute to low blood pressure. For instance, certain antihypertensive medications, diuretics, or medications that affect heart rhythm can lead to hypotension, especially if they are not properly balanced with his fluid status. The fact that he has experienced fluctuations in heart rate, ranging from 60 to 120 beats per minute, suggests that there may be underlying cardiac issues that need to be addressed. The presence of arrhythmias can indeed affect blood pressure, as irregular heartbeats can impair the heart's ability to pump effectively.

In terms of management, it is essential to monitor your father's blood pressure regularly and to communicate any significant changes to his healthcare provider. If his blood pressure remains persistently low, especially in conjunction with symptoms such as dizziness, fatigue, or fainting, it may be necessary to consider the addition of medications to help raise his blood pressure. However, this decision should be made by his healthcare provider, who can assess the risks and benefits based on his overall health status and current treatment plan.

Moreover, lifestyle modifications can also play a role in managing low blood pressure. Encouraging your father to stay well-hydrated, within the limits set by his healthcare team, can help maintain blood volume. Small, frequent meals may also be beneficial, as large meals can sometimes lead to postprandial hypotension (a drop in blood pressure after eating). Additionally, physical activity, as tolerated, can improve cardiovascular health and potentially help stabilize blood pressure.

In conclusion, persistent low blood pressure in dialysis patients like your father can arise from a combination of fluid management, medication effects, and underlying cardiac issues. It is crucial to work closely with his healthcare team to monitor his condition, adjust his treatment plan as necessary, and ensure that he receives the appropriate care to manage his blood pressure effectively. Regular follow-ups and open communication with his doctors will be key in addressing these challenges and improving his overall health and quality of life.

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