Groin Lumps: Connection to Cervical Pre-Cancer and Health Concerns

Inguinal mass

Thank you, doctor, for your previous response.
I mentioned earlier about Ms.
F, who has a precancerous condition related to cervical cancer.
After reading your reply, I recalled that in 2017, I had an irregularly bordered black spot in my perineal area, which I immediately had surgically excised and sent for histopathological examination.
The excised dimensions were 0.8 x 0.2 x 0.2 cm, and the pathology report stated: "The section shows moderate squamous hyperplasia (acanthosis) with mild chronic inflammation and melanin incontinence in the subepithelial stroma.
No definite papillary configuration nor definite koilocytotic atypia is seen.
Based on the histologic findings, it is insufficient for diagnosis of condyloma acuminatum, although the possibility of an incipient lesion cannot be excluded." The results seemed benign, so I did not pay much attention to it, but it has suddenly come to mind now.
Is there any connection between this and the swelling sensation in my groin lymph nodes? I have been feeling that the two sides of my groin are not quite the same, but if it were a malignant tumor or metastatic disease, is it possible for the lymph nodes to remain unchanged for four years?

F, 30~39 year old female. Ask Date: 2021/03/26

Dr. Cao Guotao reply Obstetrics and Gynecology

Hello, it should be fine.
Wishing you good health.

Reply Date: 2021/03/26

More Info

Understanding groin lumps and their potential connection to cervical pre-cancer can be a source of anxiety, especially for individuals with a history of cervical dysplasia or other related conditions. Your concerns about the irregular black spot you had in the perineal area and the current sensation of groin lumps are valid and warrant a thorough understanding.

First, let's clarify the findings from your previous biopsy in 2017. The report indicated moderate squamous hyperplasia with mild chronic inflammation and melanin incontinence, which suggests that there was some abnormal growth of the squamous cells but no definitive signs of malignancy or condyloma acuminatum (a type of genital wart caused by HPV). The absence of koilocytic atypia, which is often associated with HPV infection, further supports that there was no active HPV-related lesion at that time. However, the report also mentioned that the possibility of an incipient lesion could not be excluded, indicating that close monitoring is essential.

Now, regarding your current symptoms of groin lumps, it is important to understand that lymph nodes in the groin area can become enlarged for various reasons, including infections, inflammation, or malignancies. In the context of cervical pre-cancer, it is crucial to note that cervical cancer can spread to nearby lymph nodes, including those in the groin. However, it is also common for lymph nodes to react to benign conditions, such as infections or localized inflammation, which can cause them to swell.

The fact that you have been experiencing this sensation for four years without significant changes is somewhat reassuring. Malignant tumors typically cause more rapid and pronounced changes in lymph nodes, such as increased size, firmness, and tenderness. If the lymph nodes were involved in a malignant process, one would generally expect to see more pronounced symptoms over time. However, it is essential to keep in mind that each case is unique, and the behavior of lymph nodes can vary.

Given your history of cervical dysplasia and the current concerns about groin lumps, it is advisable to consult with a healthcare professional who can perform a thorough examination. This may include imaging studies, such as an ultrasound or CT scan, to assess the lymph nodes' characteristics and determine if further evaluation, such as a biopsy, is necessary. Additionally, if there are any changes in your cervical health or if you have not had recent screenings, it may be prudent to schedule a Pap smear and HPV testing to ensure that any potential issues are identified early.

In summary, while there may be a connection between your past cervical health and current groin symptoms, it is essential to approach this situation with a comprehensive evaluation. The presence of groin lumps does not automatically indicate malignancy, especially given the duration of your symptoms. However, due diligence in monitoring your health and seeking professional advice is crucial for your peace of mind and overall well-being. Regular follow-ups and screenings are vital components of managing your health, especially with a history of cervical dysplasia.

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