Fecal occult blood test (FOBT)
Recently, a child had blood streaks in their stool.
After a consultation, a stool sample was collected, and an immunochemical fecal occult blood test was performed specifically on the areas with blood streaks.
The results came back positive, but it seems that the fecal occult blood test is designed to detect blood that is not visible to the naked eye.
Is it necessary to perform the test again on normal stool? Additionally, what do the values of the occult blood test indicate?
Niming, 30~39 year old female. Ask Date: 2021/03/28
Dr. Xiao Kaiwen reply Pediatrics
Fecal occult blood testing means that if there is blood in the stool, it can be detected even in very small amounts that are not visible to the naked eye.
If the amount of blood is large enough to be seen, the fecal occult blood test will certainly be positive.
Therefore, there is no need to repeat the test when the stool appears normal.
The immunological method used in this test has a high specificity for human blood and will not yield false positives due to animal blood (such as from consuming pig or duck blood) or iron supplements.
Thus, a positive result in the immunological fecal occult blood test indicates the presence of human blood in the stool, and further evaluation by a pediatric gastroenterologist is necessary to determine the underlying cause.
Reply Date: 2021/03/28
More Info
Fecal occult blood tests (FOBT) are important diagnostic tools used to detect hidden (occult) blood in the stool, which can be an indicator of various gastrointestinal issues, including polyps, ulcers, or even cancers. In pediatric patients, the presence of blood in the stool can be particularly concerning, as it may signal underlying health issues that require further investigation.
In your case, since your child had visible blood in the stool and the FOBT returned positive, it is essential to understand the implications of these results. A positive FOBT indicates that there is blood present in the stool that is not visible to the naked eye. This can be due to a variety of reasons, including but not limited to:
1. Gastrointestinal bleeding: This could be from conditions such as hemorrhoids, anal fissures, or more serious conditions like inflammatory bowel disease (IBD) or tumors.
2. Dietary factors: Certain foods, such as red meat, can sometimes lead to false positives in FOBT due to their heme content.
3. Medications: Some medications can also affect the results of the test.
Given that your child had a positive test result, it is advisable to follow up with a healthcare provider, preferably a pediatric gastroenterologist. They may recommend additional testing, such as a repeat FOBT, endoscopy, or imaging studies, to determine the source of the bleeding. It is crucial not to dismiss the positive result, especially since it follows an episode of visible blood in the stool.
Regarding your question about whether to repeat the test, it may be beneficial to conduct another FOBT using a fresh stool sample. This can help confirm whether the initial positive result was a true indication of bleeding or if it was influenced by dietary factors or other variables. However, the decision to retest should be guided by your child's healthcare provider, who can assess the overall clinical picture and recommend the most appropriate course of action.
In summary, a positive FOBT in a pediatric patient warrants further investigation to rule out serious conditions. The test is designed to detect blood that is not visible, and while it can sometimes yield false positives, it is essential to take the results seriously, especially in the context of your child's symptoms. Consulting with a specialist will provide clarity and ensure that any necessary interventions are taken promptly.
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