Is It Normal to Have Reduced Menstrual Flow After Trigger Shot?

Is it normal for my menstrual flow to decrease significantly or almost stop after receiving a GnRH agonist injection?

Hello Dr.
Tsao: I underwent an egg freezing procedure.
On April 3rd, I had my first day of menstruation and had blood drawn for testing.
After the results, I started administering Gonal-F ovulation injections in the evening.
The next day, my menstrual flow was very light, almost nonexistent.
Is this normal? The hospital is closed for a holiday, and I won't be able to see a doctor until Tuesday, so I can't consult with my original hospital.
I'm unsure whether I should continue with the ovulation injections.
Thank you.
P.S.
I have polycystic ovary syndrome, my menstrual cycle is about 35 days, and I have regular periods that last about seven days without any previous issues of suddenly missing a period.

Linlin, 30~39 year old female. Ask Date: 2021/04/04

Dr. Cao Guotao reply Obstetrics and Gynecology

Hello, everything should be normal, please continue with the injections.
Wishing you good health.

Reply Date: 2021/04/04

More Info

It is not uncommon for women undergoing fertility treatments, such as ovarian stimulation with trigger shots, to experience changes in their menstrual flow. The situation you described, where your menstrual flow significantly reduced or almost ceased after receiving the trigger shot (Gonadotropin), can be attributed to several factors related to hormonal changes and the effects of the medication.

Firstly, the trigger shot is designed to stimulate the ovaries to produce eggs, and it often contains hormones that can alter the normal menstrual cycle. In your case, since you have polycystic ovary syndrome (PCOS), your hormonal balance is already affected, which can lead to irregularities in your menstrual cycle. The medications used in fertility treatments can further influence this balance, potentially leading to a lighter menstrual flow or even a temporary cessation of menstruation.

It is essential to understand that the hormonal changes induced by the trigger shot can suppress the natural menstrual cycle. The body may prioritize the ovarian stimulation process over the regular shedding of the uterine lining, which is what typically occurs during menstruation. This suppression can result in a lighter period or a missed period altogether.

Given that you mentioned your menstrual cycle is usually around 35 days and that you have not experienced sudden changes in your menstrual flow before, it is reasonable to consider this as a temporary effect of the medication. However, it is crucial to monitor your symptoms and any other changes you may experience.

As for whether you should continue with the trigger shots, it is best to wait for your scheduled appointment to discuss this with your healthcare provider. They will have the most accurate understanding of your treatment plan and can provide personalized advice based on your specific situation. If you experience any concerning symptoms, such as severe pain, unusual bleeding, or other significant changes, it would be advisable to seek medical attention sooner.

In summary, while it is not unusual to experience reduced menstrual flow after a trigger shot, especially in the context of PCOS and hormonal treatments, it is essential to communicate with your healthcare provider about your concerns. They can provide guidance on how to proceed with your treatment and ensure that you are on the right track for your fertility goals.

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