Myocardial Perfusion Imaging: Insights on Mild Coronary Stenosis - Cardiology

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Examination Report


Hello Dr.
Wu, the following is my report on the myocardial perfusion imaging.
Is there mild vascular stenosis? Thank you for your response.
The Tl-201 myocardial perfusion SPECT scintigraphy was performed 5 minutes after intravenous injection of 2.5 mCi Tl-201 with dipyridamole intervention (0.56 mg/kg over 4 minutes for stress) and at 4 hours after redistribution (rest).
Findings: Chest discomfort was noted during the stress test.
There is a partial reversible perfusion defect in the apical anteroseptal wall and lateral wall.
Reverse redistribution (Type II) is observed in the apicoanterior wall.
The extent of stress and rest defects is 5% and 7%, respectively.
The transient ischemic dilatation (TID) ratio is 0.99, with a normal reference value of less than 1.22.
Impression: Myocardial ischemia in the apical anteroseptal wall and lateral wall is suspected.
Myocardial ischemia in the apicoanterior wall with compensated perfusion from collaterals during stress cannot be ruled out.

Guo Ge, 50~59 year old female. Ask Date: 2021/04/10

Dr. Wu Xueming reply Cardiology


The examination results indicate that there is mild hypoxia in your myocardium.
Please visit the cardiology outpatient clinic for treatment.

Reply Date: 2021/04/10

More Info


Understanding myocardial perfusion imaging (MPI) is crucial for assessing coronary artery disease (CAD), particularly in cases of suspected mild coronary stenosis. Your report indicates that a Tl-201 myocardial perfusion SPECT scan was performed, which is a standard procedure for evaluating myocardial blood flow and identifying areas of ischemia.

In your findings, you mentioned experiencing chest discomfort during the stress test, which is a common symptom associated with myocardial ischemia. The key findings from your scan include a partial reversible perfusion defect in the apical anteroseptal wall and lateral wall, as well as reverse redistribution in the apicoanterior wall. The extent of the stress and rest defects was reported as 5% and 7%, respectively, which suggests that there is a mild degree of perfusion abnormality.

The TID (Transient Ischemic Dilation) ratio of 0.99 is also noteworthy. A TID ratio less than 1.22 is considered normal, indicating that there is no significant stress-induced dilation of the left ventricle, which can be a sign of severe ischemia. Your results suggest that while there is some degree of ischemia present, it is likely mild, given the relatively low percentages of perfusion defects and the normal TID ratio.

The impression of suspected myocardial ischemia in the apical anteroseptal wall and lateral wall indicates that there may be some degree of coronary artery stenosis, but the findings do not suggest severe obstruction. The mention of compensated perfusion from collaterals during stress implies that your heart may be receiving blood supply from alternative pathways, which can occur when primary coronary vessels are narrowed but not completely blocked.

In terms of clinical implications, mild coronary stenosis can often be managed with lifestyle modifications, medication, and regular monitoring. However, it is essential to discuss these findings with your cardiologist, who can provide a comprehensive evaluation based on your overall clinical picture, including risk factors such as age, family history, and any symptoms you may be experiencing.

In summary, your MPI results indicate mild ischemia, which could suggest mild coronary stenosis. The absence of significant inducible ischemia and the normal TID ratio are reassuring signs. Nevertheless, it is crucial to follow up with your healthcare provider to determine the best course of action, which may include further diagnostic testing, lifestyle changes, or medical management to reduce the risk of progression to more severe coronary artery disease. Regular follow-up and monitoring are key components in managing heart health, especially in the context of mild coronary stenosis.

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