Myocardial Perfusion Scan Results in Coronary Artery Disease - Cardiology

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Coronary artery disease, seeking advice on the results of a cardiac nuclear scan?


Examination Item: Tl-201 Myocardial Perfusion Scan
1.
Stress Imaging: The stress imaging following intravenous infusion of dipyridamole and the post-dipyridamole SPECT images revealed moderate hypoperfusion over the apical septo-anterior and septal walls of the left ventricle (estimated extent: 30% of the left anterior descending artery territory).
2.
Resting Imaging: Compared to the stress images, the 4-hour redistribution images revealed partial reperfusion to the aforementioned area.
Conclusion:
1.
The current study demonstrated partially reversible, moderate hypoperfusion over the apical septo-anterior wall of the left ventricle, suggesting mild coronary artery disease involving the left anterior descending artery territory.
Clinical evaluation is recommended.
2.
We would like to follow up closely.
I would like to ask the physician if there is a need for coronary angiography based on these report findings.

P.S.
The exercise electrocardiogram test was also positive for ischemia.

A Mu, 30~39 year old female. Ask Date: 2022/05/14

Dr. Huang Yinghe reply Cardiology


Hello: The nuclear medicine examination shows moderate myocardial perfusion reduction, and the exercise electrocardiogram is also positive, indicating a certain degree of myocardial hypoxia, commonly associated with coronary artery stenosis (but these two tests cannot definitively determine if there is a vascular issue).
To confirm the degree of coronary artery stenosis, a coronary angiogram is the most definitive method.
However, it is more important to address lifestyle and physical condition related to coronary artery stenosis.
It is advisable to make improvements, such as increasing fruit and vegetable intake, maintaining an exercise routine, and quitting smoking if applicable.
Additionally, if there are issues with hypertension, diabetes, or hyperlipidemia, medications should be taken as directed by a physician.
Generally, if there are no symptoms, a coronary angiogram may not be necessary.
If lifestyle adjustments have been made and medications are being taken, but symptoms such as chest tightness or shortness of breath persist, a coronary angiogram is recommended to confirm whether there is vascular stenosis.
If vascular issues are found, a coronary angiogram can also facilitate immediate treatments such as stent placement.

Reply Date: 2022/05/14

More Info


Understanding the results of a myocardial perfusion scan, especially in the context of coronary artery disease (CAD), is crucial for determining the appropriate management and treatment options for patients. The Tl-201 myocardial perfusion scan is a non-invasive imaging technique that assesses blood flow to the heart muscle during stress and at rest, providing valuable insights into the presence and severity of CAD.

In your case, the stress imaging following dipyridamole infusion revealed moderate hypoperfusion in the apical septo-anterior and septal walls of the left ventricle, estimated to involve about 30% of the left anterior descending (LAD) artery territory. This finding indicates that there is a significant reduction in blood flow to these areas of the heart muscle during stress, which is suggestive of ischemia. The resting images showed partial reperfusion, meaning that while some blood flow returned to these areas after the stress was removed, it did not fully normalize. This pattern is characteristic of partially reversible ischemia, which is often seen in patients with CAD.

The conclusion of your report indicates that there is mild CAD involving the LAD territory. Given that the stress test was also positive for ischemia, this further supports the need for careful evaluation and potential intervention. The presence of moderate hypoperfusion suggests that there may be significant stenosis (narrowing) in the coronary arteries, particularly in the LAD, which could lead to more severe ischemic events if left untreated.

Regarding the necessity for coronary angiography (heart catheterization), this is typically recommended when there is a strong suspicion of significant coronary artery disease based on non-invasive testing results, especially if the patient exhibits symptoms such as chest pain or has risk factors for CAD. The decision to proceed with catheterization should be made in consultation with your cardiologist, who will consider your overall clinical picture, including symptoms, risk factors, and the results of other tests such as the exercise electrocardiogram (ECG) that you mentioned was also positive for ischemia.

In summary, your myocardial perfusion scan results indicate the presence of moderate hypoperfusion consistent with mild CAD, particularly in the LAD territory. Given the positive findings from both the perfusion scan and the exercise ECG, it would be prudent to discuss the potential need for coronary angiography with your cardiologist. This invasive procedure can provide a definitive assessment of the coronary arteries and help guide further treatment, which may include lifestyle modifications, medical therapy, or even revascularization procedures such as angioplasty or bypass surgery, depending on the severity and extent of the disease.
It is essential to maintain open communication with your healthcare provider to ensure that all aspects of your cardiovascular health are thoroughly evaluated and managed appropriately. Regular follow-ups and adherence to prescribed treatments can significantly improve outcomes for patients with coronary artery disease.

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