Medication Side Effects: Dizziness and Nausea from Common Gastro Drugs - Gastroenterology and Hepatology

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Drug side effects


I would like to ask the doctor, a few weeks ago I experienced symptoms such as daily bloating, occasional stomach pain, and nausea before bedtime.
I visited three clinics for medication, but I did not recover.
Yesterday, I went to a clinic for an endoscopy, and the doctor diagnosed me with gastroesophageal reflux disease (GERD) and prescribed medication.
I am unsure if taking lansoprazole is causing me to feel dizzy and nauseous.
Additionally, I have been prescribed mosapride, domperidone, and magnesium oxide.
Are there any side effects from these medications that could easily cause dizziness and nausea?

Chole, 10~19 year old female. Ask Date: 2021/04/11

Dr. Cai Anshun reply Gastroenterology and Hepatology


Hello: You can try discontinuing mosapride and domperidone first.
If there is no improvement, you may return to the gastroenterology department at Changhua Hospital for further evaluation of your health.
Dr.
Tsai An-Shun.

Reply Date: 2021/04/11

More Info


When it comes to understanding the side effects of medications used for gastrointestinal issues, it’s essential to consider how these drugs interact with the body and their potential adverse effects. In your case, you mentioned experiencing symptoms such as dizziness, nausea, and gastric discomfort after taking medications including lansoprazole, mosapride, domperidone, and magnesium oxide. Let’s break down these medications and their potential side effects.

Lansoprazole is a proton pump inhibitor (PPI) commonly used to treat gastroesophageal reflux disease (GERD) and other acid-related disorders. While it is effective in reducing stomach acid, some patients report side effects such as dizziness, nausea, and abdominal pain. The dizziness you are experiencing could be related to the medication, especially if you are sensitive to changes in your body's chemistry due to the reduction of stomach acid.

Mosapride is a prokinetic agent that enhances gastrointestinal motility. It is often prescribed to alleviate symptoms of functional dyspepsia and GERD. While mosapride is generally well-tolerated, some individuals may experience side effects such as dizziness, headache, and gastrointestinal disturbances. If you are already feeling nauseous, the addition of mosapride could exacerbate this symptom.

Domperidone is another medication that promotes gastric emptying and is used to treat nausea and vomiting. Although it is effective for these purposes, it can also lead to side effects such as dizziness, dry mouth, and abdominal cramps. The risk of dizziness may increase if you are taking multiple medications that affect the gastrointestinal system.

Magnesium oxide is often used as a supplement to manage magnesium deficiency and can also act as an antacid. While it is generally safe, excessive intake can lead to gastrointestinal side effects, including diarrhea and abdominal discomfort, which may contribute to feelings of nausea.

Given your symptoms of dizziness and nausea, it is crucial to evaluate the combination of these medications. Polypharmacy, or the use of multiple medications, can increase the risk of side effects and interactions. It is also possible that your underlying condition, such as GERD, may be contributing to your symptoms, as the discomfort and nausea can be exacerbated by the medications intended to treat them.

To address your concerns, here are some recommendations:
1. Consult Your Physician: It is essential to discuss your symptoms with your healthcare provider. They may consider adjusting your medication regimen or switching to alternatives that may have a lower risk of causing dizziness and nausea.

2. Monitor Your Symptoms: Keep a detailed record of your symptoms, including when they occur and their severity. This information can help your doctor make informed decisions about your treatment.

3. Hydration and Diet: Ensure you are staying hydrated and consider dietary adjustments that may help alleviate your symptoms. Avoiding heavy, spicy, or acidic foods can sometimes reduce gastric discomfort.

4. Consider Timing of Medications: Sometimes, the timing of medication intake can influence side effects. Discuss with your physician whether taking medications at different times of the day might help reduce your symptoms.

5. Lifestyle Modifications: Implementing lifestyle changes such as elevating the head of your bed, avoiding late meals, and practicing stress-reduction techniques can also help manage GERD symptoms.

In conclusion, while the medications you are taking can be effective for treating gastrointestinal issues, they may also contribute to side effects such as dizziness and nausea. It is crucial to work closely with your healthcare provider to find the most suitable treatment plan tailored to your needs.

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