Mildly Elevated White Blood Cell Count: What You Need to Know - Family Medicine

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Slightly elevated white blood cell count?


Hello Doctor, I recently had a health check-up at my company and found that my white blood cell count is slightly elevated.
My mother has a history of leukemia (AML) and my father has a history of ventricular fibrillation.
I would like to inquire about what I should be aware of given my current slightly elevated state.
I also have a family history of hereditary diseases and high cholesterol, for which I am taking a chronic prescription medication, atorvastatin.
My health check-up reports from last year and this year (April 2021) are as follows:
- Neutrophil count: Last year 69.7, this year 71.1 (Normal Range: 35-70%)
- Hemoglobin: Last year 12.0, this year 11.9 (Normal Range: 12-16)
- Hematocrit (HCT): Last year 37.1, this year 36.8 (Normal Range: 38-47)
Is there anything specific I should pay attention to regarding these results? Most of my other values are normal.
Thank you.

Maggiema, 30~39 year old female. Ask Date: 2021/04/23

Dr. Liao Yaopan reply Family Medicine


Hello, health check data still needs to be combined with a comprehensive physical assessment to fully understand your condition.
Online consultations are not equivalent to in-person medical visits and cannot provide diagnoses or treatment recommendations.
Changhua Hospital cares about you.

Reply Date: 2021/04/23

More Info


When interpreting blood test results, especially in the context of mildly elevated white blood cell (WBC) counts, it is essential to consider various factors, including personal and family medical history, symptoms, and the specific values reported. In your case, you mentioned that your neutrophil count has increased slightly from last year to this year, and you have a family history of acute myeloid leukemia (AML) and other health issues.
Firstly, let's break down the significance of your blood test results. Your neutrophil percentage is slightly elevated (71.1% compared to the normal range of 35-70%). Neutrophils are a type of white blood cell that plays a crucial role in the immune response, particularly in fighting off infections. A mild increase in neutrophils can occur due to various reasons, including stress, infection, inflammation, or even physical exertion.
Your hemoglobin level (11.9 g/dL) is slightly below the normal range (12-16 g/dL), indicating mild anemia. Anemia can result from various factors, including nutritional deficiencies (like iron, vitamin B12, or folate), chronic diseases, or bone marrow issues. The hematocrit (HCT) level is also slightly low (36.8% compared to the normal range of 38-47%), which further supports the possibility of anemia.

Given your family history of AML, it is understandable to be concerned about your elevated WBC count. However, it is important to note that a mild increase in neutrophils alone does not indicate leukemia. Leukemia typically presents with more significant abnormalities in blood counts, including the presence of immature white blood cells (blasts) and other hematological changes. In your case, the absence of such findings is reassuring.

Here are some recommendations for you to consider:
1. Regular Monitoring: Since you have a family history of blood disorders, it is advisable to have regular blood tests to monitor your WBC count and other hematological parameters. This will help detect any significant changes early.

2. Consult a Hematologist: Given your concerns and family history, consulting a hematologist may provide you with more specialized insights. They can evaluate your blood tests in the context of your medical history and family background.

3. Address Anemia: Since you have mild anemia, it would be beneficial to investigate the underlying cause. Consider discussing with your healthcare provider about dietary changes or supplements that may help improve your hemoglobin levels. Foods rich in iron (like red meat, beans, and leafy greens) and vitamin B12 (like fish, meat, and dairy) can be particularly beneficial.

4. Lifestyle Modifications: Maintaining a healthy lifestyle, including a balanced diet, regular exercise, and managing stress, can positively impact your overall health and immune function.

5. Stay Informed: Educate yourself about the signs and symptoms of blood disorders. If you notice any unusual symptoms, such as unexplained bruising, fatigue, or frequent infections, seek medical attention promptly.

In summary, while your mildly elevated WBC count and slightly low hemoglobin levels warrant attention, they do not necessarily indicate a serious condition like leukemia, especially in the absence of other concerning findings. Regular monitoring and consultation with healthcare professionals will be key in managing your health effectively.

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