Gallbladder Polyps: Risks and Monitoring Guidelines - Gastroenterology and Hepatology

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Gallbladder polyp


Hello, Doctor! I would like to ask about my father's gallbladder polyp.
At the end of 2018, he underwent a comprehensive health check and was found to have a 1.2 cm gallbladder polyp.
He has been monitored every three months for about two to three times, and there has been no increase in size.
In early 2020, he had another follow-up, and there were still no changes.
However, he has not had a follow-up this year yet (he currently has no symptoms).
Is it possible that it could have progressed to gallbladder cancer in this past year and a half? I feel a bit anxious since it has been a while since the last follow-up.
Thank you for your response, Doctor!

Mr. Wang, 20~29 year old female. Ask Date: 2021/04/25

Dr. Chen Shidian reply Gastroenterology and Hepatology


There is still a chance of enlargement/worsening; please seek medical follow-up.

Reply Date: 2021/04/25

More Info


Gallbladder polyps are growths that protrude from the lining of the gallbladder. They are relatively common and are often discovered incidentally during imaging studies, such as ultrasounds or CT scans. The majority of gallbladder polyps are benign, with cholesterol polyps being the most common type. However, there is a small risk that certain types of polyps, particularly those larger than 1 cm, can be precursors to gallbladder cancer.

In your father's case, the 1.2 cm gallbladder polyp has been stable over multiple follow-ups, which is a positive sign. The fact that it has not changed in size over the past couple of years suggests that it is less likely to be malignant. Generally, gallbladder polyps that remain stable in size for an extended period are less concerning than those that grow rapidly.
The risk of a gallbladder polyp turning into cancer is influenced by several factors, including the size of the polyp, its appearance on imaging studies, and the patient's overall health and risk factors. Polyps larger than 1 cm have a higher risk of malignancy, and those that exhibit certain characteristics (such as irregular borders or a solid appearance) may warrant closer monitoring or even surgical intervention.

Monitoring guidelines typically recommend that polyps larger than 1 cm be followed up with imaging studies every 6 to 12 months. If a polyp remains stable, the frequency of follow-up can often be reduced. For polyps smaller than 1 cm, follow-up is usually less frequent, often every 2 to 3 years, unless there are changes in symptoms or new findings.

In your father's case, since the polyp has not changed in size and he is currently asymptomatic, it is understandable to feel anxious about the time elapsed since the last follow-up. However, the absence of symptoms is reassuring. It is advisable to schedule a follow-up ultrasound or imaging study to reassess the polyp, especially since it has been over a year since the last evaluation. This will help to ensure that there are no changes that could indicate a progression towards malignancy.

In summary, while there is a small risk of gallbladder cancer associated with polyps, the stability of your father's polyp over time is encouraging. Regular monitoring is essential, and it would be prudent to arrange for a follow-up examination to provide peace of mind and ensure that any potential changes are detected early. If there are any new symptoms, such as abdominal pain, jaundice, or changes in appetite, it is important to seek medical attention promptly.

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