Watery Discharge After Long-Acting Menopause Injection - Obstetrics and Gynecology

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Hello Doctor: To prevent the recurrence of chocolate cysts, I am currently receiving long-acting (3-month) menopause injections as treatment.
Recently, I have noticed that in addition to experiencing symptoms similar to menopause, I also have watery discharge (though it's not much).
Is this a result of the menopause injection? Do I need to return for a check-up? Thank you for taking the time to respond.

Viki, 30~39 year old female. Ask Date: 2021/04/26

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, just observe for now.
If the amount is significant, then it is advisable to consult a gynecologist.
Wishing you good health.

Reply Date: 2021/04/26

More Info


When considering the use of long-acting menopause injections, it is important to understand both the intended effects and potential side effects. These injections, often containing hormones such as depot medroxyprogesterone acetate (DMPA), are used to manage symptoms associated with menopause and to prevent conditions like endometriosis or the recurrence of ovarian cysts, such as chocolate cysts.

One common concern among patients receiving these injections is the occurrence of abnormal vaginal discharge, which can manifest as watery discharge. This symptom can be attributed to hormonal changes induced by the injection. Hormonal therapies can lead to alterations in the vaginal flora and mucosal lining, resulting in changes in discharge consistency and volume. In many cases, this is a benign side effect and may resolve as the body adjusts to the hormonal changes.

However, it is crucial to differentiate between normal side effects and signs of potential complications. If the watery discharge is accompanied by other symptoms such as a strong odor, itching, burning sensations, or any signs of infection (like fever or pelvic pain), it would be advisable to seek medical attention. These could indicate a vaginal infection or other underlying issues that may require treatment.

In your case, since you are experiencing watery discharge alongside menopausal symptoms, it is likely related to the hormonal changes from the long-acting injection. However, if this symptom persists or worsens, or if you have any concerns about your health, it is always best to consult your healthcare provider. They can perform a thorough examination and possibly conduct tests to rule out any infections or other complications.

Additionally, it is important to maintain regular follow-ups with your healthcare provider while on long-acting hormonal treatments. They can monitor your response to the medication, manage any side effects, and adjust your treatment plan as necessary. Regular check-ups are especially important if you have a history of conditions like chocolate cysts, as they can help ensure that any potential recurrence is caught early.

In summary, while watery discharge can be a common side effect of long-acting menopause injections due to hormonal changes, it is essential to monitor your symptoms closely. If you experience any concerning signs or if the discharge does not resolve, do not hesitate to reach out to your healthcare provider for further evaluation and guidance. Your health and comfort during this transition are paramount, and your provider can help navigate any challenges you may face.

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