Painful Blister on Right Side of Tongue: Possible Causes and Solutions - Otolaryngology

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A blister has formed on the right edge of the tongue?


Hello, doctor.
During lunch today, I suddenly felt pain on the right side of my tongue.
When I looked in the mirror, I noticed that the right side was noticeably more swollen, and after taking a photo with my phone, I discovered a blister had formed.
I took a few pictures and would like to consult with you, as it's inconvenient for me to see a doctor while I'm abroad.
Thank you for your help! I found some information online and I'm worried it might be a herpes virus, as I have herpes on my hands and feet.

Miss Chen, 30~39 year old female. Ask Date: 2021/05/03

Dr. Zheng Jueyi reply Otolaryngology


Hello: It is common to have inflammation of the tongue.
Whether the small blisters are due to a herpes virus infection cannot be determined at this time.
It is recommended to drink plenty of water and avoid irritating foods.
If the symptoms persist for more than two weeks or if they continue to grow and cause pain, it is advisable to seek medical evaluation.
Wishing you safety and health.
Sincerely, Dr.
Cheng Jue-Yi, Director of the Department of Otolaryngology, Taoyuan Hospital, Ministry of Health and Welfare.

Reply Date: 2021/05/03

More Info


The sudden appearance of a painful blister on the right side of your tongue can be concerning, especially when accompanied by swelling and discomfort. There are several potential causes for this condition, and understanding them can help you determine the best course of action.

One common cause of blisters on the tongue is oral herpes, which is caused by the herpes simplex virus (HSV). This virus can lead to painful sores and blisters, typically associated with a tingling or burning sensation before the blister appears. If you have a history of herpes simplex infections on other parts of your body, such as your hands or feet, it is possible that the virus could manifest in your oral cavity as well. However, oral herpes typically presents with multiple lesions rather than a single blister.

Another possibility is aphthous ulcers, also known as canker sores. These are small, painful lesions that can occur on the tongue, inside the cheeks, or on the gums. The exact cause of these ulcers is not well understood, but they are often triggered by stress, certain foods (like citrus or spicy foods), or nutritional deficiencies (such as vitamin B12, folate, or iron). Unlike herpes, canker sores are not contagious.

Additionally, the blister could be a result of trauma or irritation. If you accidentally bit your tongue or if you have been consuming very hot or spicy foods, this could lead to localized swelling and blistering. Similarly, dental appliances, such as braces or ill-fitting dentures, can cause irritation and result in blisters.

Allergic reactions to certain foods or dental products may also lead to swelling and blistering of the tongue. If you have recently introduced a new food or oral hygiene product, this could be a potential cause.

In terms of treatment, the approach will depend on the underlying cause:
1. For oral herpes, antiviral medications such as acyclovir can help reduce the severity and duration of the outbreak. Over-the-counter topical treatments may also provide some relief.

2. For aphthous ulcers, topical anesthetics can help alleviate pain, and avoiding spicy or acidic foods may prevent further irritation. In some cases, a healthcare provider may prescribe corticosteroids to reduce inflammation.

3. If the blister is due to trauma or irritation, maintaining good oral hygiene and avoiding further irritation is key. Rinsing with warm salt water can promote healing and reduce discomfort.

4. For allergic reactions, identifying and avoiding the allergen is crucial. Antihistamines may help alleviate symptoms.

Given your concern about the herpes virus, it is advisable to consult a healthcare professional for an accurate diagnosis and appropriate treatment. If you notice any signs of systemic infection, such as fever or widespread lesions, seek medical attention promptly.

In summary, while a painful blister on the tongue can arise from various causes, including herpes, canker sores, trauma, or allergic reactions, proper diagnosis and treatment are essential for effective management. If you are currently abroad and unable to see a doctor, consider reaching out to a telehealth service for guidance.

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