Water Intoxication: Causes and Risks of Overhydration - Internal Medicine

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Water intoxication


What is water intoxication, and why can drinking water lead to poisoning?

Qǐngwèn, 20~29 year old female. Ask Date: 2003/03/17

Dr. Xie Yonghui reply Internal Medicine


Water intoxication may be caused by: (1) psychogenic polydipsia; (2) lesions in the thirst center; (3) administration of hypotonic IV solutions to patients who are unable to dilute their urine normally (e.g., postoperative patients or those with renal insufficiency).
If the patient develops severe symptomatic hyponatremia (for example, serum sodium concentration less than 110-115 mEq/L, along with symptoms such as drowsiness, altered mental status, seizures, or coma), urgent treatment is required, including the use of diuretics and supplementation of sodium and potassium.
Treatment for psychogenic polydipsia includes reassurance and psychiatric counseling.
Regardless of the cause of water intoxication, until the patient's serum sodium concentration returns to normal, we must restrict fluid intake (500-1000 mL per day) and discontinue the use of hypotonic solutions.

Reply Date: 2003/03/17

More Info


Water intoxication, also known as hyperhydration or water poisoning, occurs when an individual consumes an excessive amount of water in a short period, leading to an imbalance of electrolytes in the body, particularly sodium. This condition can result in a dangerous drop in sodium levels in the blood, known as hyponatremia. Understanding the causes and risks associated with water intoxication is crucial for preventing this potentially life-threatening condition.


Causes of Water Intoxication
1. Psychogenic Polydipsia: This is a psychological condition where an individual feels an uncontrollable urge to drink excessive amounts of water. It is often seen in patients with psychiatric disorders, such as schizophrenia.

2. Thirst Center Lesions: Damage to the brain's thirst center can lead to inappropriate thirst signals, causing individuals to drink more water than necessary.

3. Hypotonic IV Solutions: Patients receiving intravenous fluids that are hypotonic (lower concentration of solutes than blood) may be at risk, especially if they have impaired kidney function or are unable to excrete water effectively. This is common in postoperative patients or those with renal insufficiency.

4. Endurance Sports: Athletes, particularly those participating in endurance events, may consume large quantities of water without adequate electrolyte replacement, leading to an imbalance.


Symptoms of Water Intoxication
The symptoms of water intoxication can vary but often include:
- Headache: Due to swelling of brain cells (cerebral edema).

- Nausea and Vomiting: As the body attempts to rid itself of excess water.

- Confusion or Disorientation: Resulting from altered brain function due to electrolyte imbalance.

- Seizures: In severe cases, due to significant changes in brain chemistry.

- Coma: In extreme situations, where brain function is severely compromised.


Risks of Water Intoxication
The primary risk associated with water intoxication is the development of hyponatremia. When sodium levels drop below normal (typically below 135 mEq/L), it can lead to serious complications, including:
- Cerebral Edema: Swelling of the brain, which can increase intracranial pressure and lead to brain damage.

- Respiratory Distress: In severe cases, fluid can accumulate in the lungs, leading to difficulty breathing.

- Cardiac Issues: Electrolyte imbalances can affect heart function, potentially leading to arrhythmias.


Prevention and Management
To prevent water intoxication, it is essential to:
- Monitor Fluid Intake: Be aware of how much water you are consuming, especially during physical activities or in hot weather.

- Balance Electrolytes: When engaging in prolonged exercise, consider electrolyte-replenishing drinks rather than just water.

- Listen to Your Body: Pay attention to thirst cues and avoid forcing yourself to drink excessive amounts of water.

If someone is suspected of experiencing water intoxication, immediate medical attention is necessary. Treatment may involve:
- Restricting Fluid Intake: Limiting water consumption to allow sodium levels to stabilize.

- Administering Hypertonic Saline: In severe cases, a healthcare provider may administer a hypertonic saline solution to correct sodium levels.

- Diuretics: Medications may be used to help the body excrete excess water.

In conclusion, while water is essential for life, excessive consumption can lead to severe health risks, including water intoxication. Understanding the causes, symptoms, and preventive measures is vital for maintaining a healthy balance of hydration and electrolyte levels in the body. Always consult a healthcare professional if you suspect you or someone else may be experiencing symptoms of water intoxication.

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