A acid
Hello, due to my long-standing severe acne issues, I was recently referred by a friend to a clinic in Taichung City, where the doctor prescribed me isotretinoin (brand name Roaccutane) at a dosage of 20mg.
Additionally, I need to take the anti-inflammatory medication doxycycline at 100mg.
Could you please inform me about the side effects of these medications and whether I need any additional skincare during the treatment period?
Wow, 10~19 year old female. Ask Date: 2003/03/17
Dr. Zhang Xiaolin reply Pharmacology
Hello: Roaccutane (isotretinoin) is used for the treatment of more severe acne.
This medication normalizes skin keratinization, suppresses sebaceous gland activity, reduces sebum viscosity, and decreases follicular obstruction.
Side effects may include headache, fatigue, cheilitis, dry skin, photosensitivity, and elevated liver function tests (<1%), among others.
Side effects vary from person to person and do not necessarily occur in everyone, so there is no need to be overly concerned.
Medical advice: 1.
If you experience muscle pain, please report it to your physician immediately.
2.
Do not take vitamin A or its derivatives, as they may increase toxicity.
3.
This medication is teratogenic and is contraindicated in pregnant women.
4.
The treatment course is relatively long, and liver function should be monitored once a month.
Care instructions: 1.
This medication causes photosensitivity; avoid sun exposure.
2.
Avoid staying up late, high-calorie foods (chocolate, peanuts, butter), as well as spicy and fried foods, and consume more fresh fruits and vegetables.
Reply Date: 2003/03/17
More Info
Roaccutane, known generically as isotretinoin, is a powerful medication primarily used to treat severe acne, particularly nodular acne that has not responded to other treatments. While it can be highly effective, it is essential to be aware of its potential side effects and the necessary care tips during treatment.
Side Effects of Roaccutane
1. Skin Reactions: One of the most common side effects is dryness of the skin, lips, and eyes. Patients often experience chapped lips and may require frequent application of moisturizers and lip balms. Additionally, some individuals may notice peeling skin or increased sensitivity to sunlight, which necessitates the use of sunscreen.
2. Gastrointestinal Issues: Some patients report gastrointestinal discomfort, including nausea, diarrhea, or abdominal pain. It is advisable to take the medication with food to help mitigate these effects.
3. Musculoskeletal Pain: Joint and muscle pain can occur, particularly in physically active individuals. If you experience significant discomfort, consult your healthcare provider for advice on managing these symptoms.
4. Psychological Effects: There have been reports of mood changes, including depression and anxiety, in some patients taking isotretinoin. It is crucial to monitor your mental health closely and communicate any changes to your doctor.
5. Liver Function: Roaccutane can affect liver function, so regular blood tests are necessary to monitor liver enzymes and ensure they remain within a safe range.
6. Pregnancy Risks: Isotretinoin is highly teratogenic, meaning it can cause severe birth defects if taken during pregnancy. Women of childbearing age must use effective contraception during treatment and for at least one month after discontinuation.
Care Tips During Treatment
1. Hydration and Moisturization: Given the drying effects of Roaccutane, it is essential to stay well-hydrated and use a good quality moisturizer. Look for products that are non-comedogenic (won't clog pores) to avoid exacerbating acne.
2. Sun Protection: Use a broad-spectrum sunscreen with an SPF of at least 30. Since isotretinoin can increase photosensitivity, it is crucial to protect your skin from sunburn.
3. Regular Follow-ups: Schedule regular appointments with your dermatologist to monitor your progress and any side effects. Blood tests will likely be required to check liver function and lipid levels.
4. Avoid Certain Products: While on Roaccutane, avoid using harsh skin treatments, such as chemical peels, waxing, or abrasive scrubs, as your skin will be more sensitive.
5. Diet Considerations: While there are no specific dietary restrictions, maintaining a balanced diet can support overall health. Some patients find that avoiding alcohol can help reduce the risk of liver issues.
6. Mental Health Monitoring: Be vigilant about your mental health during treatment. If you notice any mood changes or feelings of depression, reach out to your healthcare provider immediately.
Conclusion
Roaccutane can be a life-changing treatment for severe acne, but it comes with a range of potential side effects that require careful management. By staying informed about these side effects and following the care tips outlined above, you can help ensure a safer and more effective treatment experience. Always maintain open communication with your healthcare provider throughout your treatment journey to address any concerns or side effects promptly.
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