Can Antibiotics Cause Joint Pain? Side Effects and Solutions - Orthopedics

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Can antibiotics cause joint pain?


Hello, my mother was hospitalized previously to receive antibiotics, but the more she received them, the worse she felt.
Eventually, she developed knee pain and weakness, as well as shoulder pain that hasn't improved.
She is in so much pain at night that she can't sleep and has no appetite.
Could this be a side effect of the antibiotics? If so, what should we do?

Ying Xiansheng, 30~39 year old female. Ask Date: 2021/05/12

Dr. Chen Yongxue reply Orthopedics


Hello, some antibiotics can have joint pain as a side effect, which depends on the type of antibiotic.
However, it could also be due to inflammation from knee joint degeneration.
It is advisable to visit an orthopedic clinic for evaluation.
Thank you.

Reply Date: 2021/05/12

More Info


Antibiotics are essential medications used to treat bacterial infections, but they can also have side effects that may affect various parts of the body, including the joints. In your mother's case, experiencing joint pain and weakness after receiving antibiotics could be attributed to several factors, including the specific antibiotic used, the duration of treatment, and her individual response to the medication.


Potential Side Effects of Antibiotics
1. Musculoskeletal Pain: Some antibiotics, particularly fluoroquinolones (like ciprofloxacin and levofloxacin), are known to cause musculoskeletal pain, including joint and tendon pain. This is due to their effect on collagen synthesis and tendon integrity. While your mother may not have taken a fluoroquinolone, other antibiotics can still lead to discomfort in the joints.

2. Allergic Reactions: In some cases, antibiotics can trigger allergic reactions that manifest as joint pain or swelling. If your mother has a history of allergies, this could be a possibility.

3. Disruption of Gut Flora: Antibiotics can disrupt the balance of gut bacteria, leading to gastrointestinal issues, which can indirectly affect overall health and contribute to feelings of malaise, fatigue, and even joint pain due to systemic inflammation.

4. Tendonitis: Certain antibiotics can increase the risk of tendonitis, particularly in older adults or those with pre-existing conditions. This could explain the shoulder pain your mother is experiencing.

5. Drug Interactions: If your mother is taking other medications, there could be interactions that exacerbate side effects, including joint pain.


What to Do Next
1. Consult a Healthcare Professional: The first step is to consult with your mother's healthcare provider. They can assess her symptoms, review her medication history, and determine if the antibiotics are the likely cause of her joint pain.

2. Pain Management: Over-the-counter pain relievers such as acetaminophen or ibuprofen may help alleviate her joint pain. However, it's essential to consult with a doctor before starting any new medication, especially if she has other health conditions or is taking other medications.

3. Physical Therapy: If the pain persists, physical therapy may be beneficial. A physical therapist can provide exercises to strengthen the muscles around the joints and improve mobility.

4. Hydration and Nutrition: Encourage your mother to stay hydrated and maintain a balanced diet. Proper nutrition can support her recovery and overall health.

5. Monitor Symptoms: Keep track of her symptoms, including when the pain occurs and its severity. This information can be helpful for her healthcare provider in determining the best course of action.

6. Alternative Treatments: Depending on the severity of her symptoms, alternative treatments such as acupuncture or massage therapy may provide relief.


Conclusion
While antibiotics are crucial for treating infections, they can have side effects, including joint pain. It's essential to address these symptoms with a healthcare professional to determine the underlying cause and appropriate treatment. Your mother's health and comfort are paramount, and with the right approach, her symptoms can be managed effectively.

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