Lymphadenopathy
Hello Dr.
Chen, about two weeks ago, I discovered a lump measuring 1.7 x 1.5 cm under my right clavicle.
The characteristics of the lump are that it is hard, immovable, and painless.
A week later, I went to a major hospital for an ultrasound and biopsy.
The ultrasound results indicated an irregularly shaped mass, and a biopsy was performed immediately.
The biopsy results showed lymphadenopathy of unknown origin (due to bacterial infection), and all blood test values were normal (tumor markers were not tested).
The doctor did not arrange for any further detailed examinations and mentioned that I would be followed up in a few months.
I would like to ask Dr.
Chen: 1.
Is a lymph node lump that is over 1 cm, hard, immovable, and painless likely to be benign? 2.
Is there a significant possibility that it could develop into lymphoma? 3.
In addition to the characteristics of the tumor, I also experience skin itching, sometimes leading to subcutaneous bleeding from scratching, or my entire arm swelling.
Furthermore, I tend to sweat a lot; I always end up sweating profusely when eating noodles or hot pot.
I wonder if these symptoms align with those of lymphoma? (These conditions have been long-term, and I thought they were due to allergies or hyperhidrosis.) 4.
Is there a possibility of error in the biopsy results? For example, could it have been taken from a tissue without cancer cells? I have seen responses from other doctors stating that many lymphoma patients also have normal blood test values.
If I still have concerns, what additional avenues can I pursue for more detailed examinations? I apologize for the numerous questions, and I appreciate your response, thank you.
Niming, 20~29 year old female. Ask Date: 2021/05/13
Dr. Chen Yunfang reply Oncology
Hello: 1.
I cannot respond as I am unsure about the content of the report.
2.
I have not seen the report, so I cannot answer that either.
3.
No, this is not a characteristic related to lymphoma.
4.
Without a report, I cannot answer that either.
Thank you.
Reply Date: 2021/05/13
More Info
Hello, thank you for your inquiry regarding lymph node enlargement. It's understandable to have concerns when discovering a lump, especially in the context of potential lymph node issues. Let's address your questions one by one.
1. Is a hard, immovable, and painless lymph node larger than 1 cm likely benign?
The characteristics of lymph nodes can vary widely. While a lymph node that is hard, immovable, and painless can raise suspicion, it does not automatically indicate malignancy. Many benign conditions, such as infections or inflammatory processes, can cause lymph nodes to enlarge and become firm. However, the size and characteristics you describe warrant careful monitoring and possibly further evaluation, especially given that it is over 1 cm.
2. Is there a significant risk of it becoming lymphoma?
While it is true that some lymph nodes can become malignant, the majority of enlarged lymph nodes are due to benign causes. Factors such as your age, medical history, and any accompanying symptoms (like fever, weight loss, or night sweats) play a crucial role in assessing the risk of lymphoma. The fact that your blood tests returned normal and the biopsy indicated bacterial infection suggests a lower likelihood of malignancy, but it is essential to follow up with your healthcare provider for ongoing monitoring.
3. Do my other symptoms (skin itching, bruising, excessive sweating) indicate lymphoma?
The symptoms you describe, such as skin itching and excessive sweating, are not specific indicators of lymphoma. Itching can be associated with various conditions, including allergies, skin disorders, or even stress. Excessive sweating can also be attributed to multiple factors, including hyperhidrosis, anxiety, or hormonal changes. While these symptoms can occur in some lymphoma cases, they are not definitive indicators of the disease. It’s essential to discuss these symptoms with your doctor, who can evaluate them in the context of your overall health.
4. Is there a possibility of error in the biopsy results?
While biopsy results are generally reliable, no test is infallible. There is a possibility of sampling error, where the biopsy may not capture the area of concern, especially if the lymph node has heterogeneous characteristics. However, if the pathologist has noted signs of infection, this suggests that the lymph node is responding to a process, which is often a benign reaction. If you have ongoing concerns about the accuracy of the biopsy, you may discuss the possibility of a repeat biopsy or additional imaging studies with your physician.
If you remain uneasy about your condition, seeking a second opinion from a hematologist or an oncologist could provide additional reassurance and clarity. They can offer further diagnostic options, such as advanced imaging (like PET scans) or additional laboratory tests to rule out malignancy.
In summary, while your symptoms and findings warrant careful monitoring, the current evidence suggests a benign process. Regular follow-ups with your healthcare provider are crucial to ensure any changes are promptly addressed. Remember to maintain open communication with your doctor about any new symptoms or concerns that arise. Your health and peace of mind are paramount. Thank you for reaching out, and I wish you the best in your health journey.
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