Am I at Risk for Rheumatoid Arthritis? My Joint Pain - Orthopedics

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Do I have rheumatoid arthritis?


Hello Doctor: This past week, when I wake up in the morning (not every day, about twice), I experience pain in the proximal interphalangeal joint of my right ring finger, while other joints are not painful.
The pain subsides with movement, but it hurts if I press on that spot.
Since I wasn't sure if I had bumped it, I went to see an orthopedic specialist.
They checked for rheumatoid arthritis markers, and my results were: RA (quantitative) 6.1, CRP (quantitative) 0.01, ESR 14 (1 hour).
The doctor mentioned that there is less than a 40% chance of rheumatoid arthritis because the ESR is elevated, but I found online that the standard value for ESR seems to be 0-20.
Therefore, I would like to ask you, are my values truly abnormal? What is the risk of having a disease? Thank you.

Xiao Shu, 40~49 year old female. Ask Date: 2021/06/02

Dr. Wang Shouji reply Orthopedics


Hello, rheumatoid arthritis is mostly characterized by polyarticular small joint inflammation, where multiple small joints (such as those in the fingers and toes) can become hot and painful during flare-ups.
If there is only a single joint pain, it is advisable to observe it first.
An ESR of 14 is not considered too high and falls within the normal range.
Changhua Hospital cares about your health.
Wang Shou-ji.

Reply Date: 2021/06/02

More Info


Thank you for your inquiry regarding your joint pain and the potential risk of developing rheumatoid arthritis (RA). Based on the information you've provided, it seems that you are experiencing intermittent pain in your right hand's proximal interphalangeal joint, specifically in the ring finger. You mentioned that this pain occurs occasionally upon waking and resolves with movement, which is a notable detail.

To address your concerns about the lab results: your RA quantitative value of 6.1, along with a CRP of 0.01 and an ESR of 14, indicates that while there is some elevation in the ESR, the other markers do not strongly suggest active inflammation typically associated with RA. The ESR (erythrocyte sedimentation rate) is indeed considered elevated if it exceeds the normal range, which is generally accepted as 0-20 mm/hr for men and 0-30 mm/hr for women, depending on the laboratory standards. An ESR of 14 is within the normal range, albeit on the higher side, but not significantly elevated.

The presence of joint pain, especially if it is transient and resolves with movement, could be attributed to various factors, including mechanical issues, overuse, or even early inflammatory changes. The fact that only one joint is affected and that the pain is not persistent or associated with swelling or other systemic symptoms is reassuring.
Regarding your risk for developing RA, it is important to consider several factors. RA is an autoimmune disease characterized by chronic inflammation of the joints, and its onset can be influenced by genetic predisposition, environmental factors, and hormonal changes. While you have experienced some joint pain, the current lab results do not indicate a definitive diagnosis of RA. The 40% probability mentioned by your physician suggests that while there is some concern, it is not a strong indication of RA at this time.

To further assess your risk, it may be beneficial to monitor your symptoms closely. If you experience persistent joint pain, swelling, stiffness (especially in the morning), or if the pain begins to affect multiple joints, it would be prudent to follow up with a rheumatologist. They may recommend additional tests, such as anti-CCP antibodies or rheumatoid factor, which can provide more insight into your risk for RA.

In the meantime, maintaining a healthy lifestyle, including regular exercise, a balanced diet, and adequate rest, can help support joint health. If you find that your pain worsens or becomes more frequent, do not hesitate to seek medical advice. Early intervention can be crucial in managing potential autoimmune conditions effectively.

In summary, while your current symptoms and lab results do not strongly indicate RA, it is essential to remain vigilant and consult with your healthcare provider if your condition changes. Regular follow-ups and open communication with your doctor will help ensure that any potential issues are addressed promptly. Thank you for your question, and I hope this information provides you with some clarity regarding your joint pain and risk for rheumatoid arthritis.

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