Prolonged Cough: Symptoms and Seeking Solutions - Pulmonology

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Persistent cough that has not improved?


Hello, I have been experiencing a persistent cough for over six months.
In the past, similar symptoms would resolve on their own within about a month, but this time it has lasted unusually long.
I have visited the hospital several times during this period, and both initial and recent chest X-rays showed no issues.
Lung function tests indicated that aside from a reduced vital capacity, everything else was normal.
Therefore, I would like to seek your opinion.
I often experience throat itching and coughing, with the sputum being thick, transparent, and resembling white foam.
I feel like I can never fully clear the phlegm, and even when I try to expel it, I can't seem to get rid of it completely.
When the symptoms are more severe, I feel a vibration sensation in my throat and chest, and sometimes I hear wheezing sounds while breathing.
These symptoms worsen when I lie down, especially the coughing and phlegm production, which prevents me from sleeping or causes me to wake up after one or two hours of sleep, making it difficult to fall back asleep until some time has passed.
Additionally, I experience a tight sensation in the area between my throat and collarbone, which occasionally makes breathing feel more laborious, although this happens infrequently and I do not experience wheezing.
The doctor prescribed three types of medications that provided some relief.
One is a theophylline-based bronchodilator, which alleviated many symptoms initially, but after a certain duration, it caused increased throat itching and coughing, making it worse than before.
The second is a corticosteroid (tablet), which also provided significant relief, but symptoms gradually returned after finishing the course.
The last one is an inhaled corticosteroid, which can provide immediate relief for throat itching, persistent coughing, tightness, and wheezing, but it does not achieve the same level of relief as the first two medications, especially regarding the itching and coughing.
Sometimes, even after using it, I still cough quite severely, so its effectiveness before sleep is uncertain.
Additionally, once I start using this inhaler, I find myself needing to use it more frequently, going from once a day to five or six times a day.
Initially, the doctor suggested that my symptoms might be asthma (though I do not wheeze), but more recently, they mentioned it could be bronchial hyperreactivity.
I have a history of severe nasal allergies, which cause frequent sneezing, nasal congestion, and runny nose, often lasting nearly the entire day during flare-ups.
However, since the onset of my current issues, my nasal allergy symptoms seem to have disappeared, and I am unsure if there is any connection.

To add, I have tried wearing a mask except when eating or showering, and I keep an air purifier running 24/7 in my room, but the problems and their severity remain unchanged.
I would like to ask for your opinion on what kind of condition I might have.
Should I also consult an ear, nose, and throat specialist? Do you have any other recommendations? Thank you in advance for your response.

Wu, 30~39 year old female. Ask Date: 2021/06/08

Dr. Lu Mingzhi reply Pulmonology


Hello: Based on your description, asthma is a highly likely diagnosis.
You can come to the clinic to arrange for asthma-related tests, including allergen testing.
Additionally, it is recommended to schedule sputum analysis and a CT scan to rule out other potential lung diseases.

Reply Date: 2021/06/08

More Info


Prolonged cough can be a frustrating and debilitating symptom, especially when it persists for months. Based on your description, it seems that you are experiencing a combination of respiratory symptoms, including a persistent cough, production of thick, clear phlegm, and sensations of tightness in the throat and chest. The fact that your symptoms worsen when lying down and that you experience difficulty sleeping due to coughing are significant indicators of an underlying issue that may require further investigation.

Given your history of allergies, particularly with nasal symptoms, it is possible that your prolonged cough could be related to post-nasal drip, which occurs when mucus from the nasal passages drips down the back of the throat, leading to irritation and coughing. This condition can be exacerbated by allergens, irritants, or even changes in weather. Additionally, your previous diagnosis of asthma or bronchial hyperreactivity could also play a role in your current symptoms, especially if you have a history of wheezing or difficulty breathing during episodes of coughing.

The medications you mentioned—bronchodilators, corticosteroids, and inhalers—are commonly used to manage asthma and other respiratory conditions. However, it is concerning that you have experienced worsening symptoms with the use of these medications. This could indicate that your condition is not being adequately controlled or that there may be an underlying issue that has not yet been addressed.

Here are some recommendations for managing your symptoms and seeking further evaluation:
1. Follow-Up with a Specialist: Since your symptoms have persisted for an extended period, it would be beneficial to consult with both a pulmonologist and an ear, nose, and throat (ENT) specialist. A pulmonologist can assess your lung function more thoroughly and may recommend additional tests, such as a methacholine challenge test to evaluate for asthma or a CT scan to look for structural issues in the lungs. An ENT specialist can evaluate for any nasal or sinus issues that may be contributing to post-nasal drip.

2. Consider Allergy Testing: Given your history of nasal allergies, it may be worthwhile to undergo allergy testing. Identifying specific allergens can help you avoid triggers and manage your symptoms more effectively.

3. Lifestyle Modifications: Continue using an air purifier and wearing a mask if you are in environments that may trigger your symptoms. Additionally, consider using saline nasal sprays or rinses to help clear mucus from your nasal passages and reduce post-nasal drip.

4. Hydration and Humidification: Staying well-hydrated can help thin mucus, making it easier to expel. Using a humidifier in your bedroom may also help alleviate throat irritation and coughing at night.

5. Monitor Your Symptoms: Keep a detailed diary of your symptoms, including when they occur, their severity, and any potential triggers. This information can be invaluable for your healthcare providers in diagnosing and managing your condition.

6. Avoid Irritants: Stay away from smoke, strong odors, and other environmental irritants that may exacerbate your symptoms.
7. Medication Review: Discuss with your healthcare provider the possibility of adjusting your current medications. Sometimes, a different class of medication or a combination therapy may be more effective in managing your symptoms.

In conclusion, your prolonged cough and associated symptoms warrant a comprehensive evaluation to determine the underlying cause. Collaboration between specialists, along with lifestyle modifications and careful monitoring of your symptoms, can lead to improved management and relief from your persistent cough. Don't hesitate to seek further medical advice, as timely intervention can significantly enhance your quality of life.

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