Red Spots on Glans and Milky Urethral Gland Fluid: Causes and Solutions - Urology

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Red spots on the glans and milky urethral discharge?


Hello Doctor,
I recently noticed the following: 1.
There are red spots on the glans, which worsen after masturbation or sexual activity.
2.
The bulbourethral gland secretion appears milky white (it used to be clear and colorless).
I visited the hospital, and the diagnosis was a fungal infection.
Urine culture showed bacterial growth, which was said to be skin flora, possibly due to contamination of the sample (as midstream urine was not collected).
Different doctors prescribed doxycycline and sulfamethoxazole, which I took for three weeks.
The red spots have diminished, but there is still slight redness after masturbation or sexual activity.
The bulbourethral gland secretion remains unchanged, still appearing milky white.
I have had risky sexual encounters, but tests for sexually transmitted infections were negative.

I would like to ask you: 1.
What could be the cause of this? 2.
Is there a way to confirm the type of fungal infection? 3.
Would not collecting midstream urine affect the urine test results?
Thank you, Doctor.
Wishing you good health.

Xuan, 20~29 year old female. Ask Date: 2021/06/11

Dr. Du Shixi reply Urology


Hello: 1) There are many reasons, including inadequate hygiene, humidity, and unsafe sexual practices.
2) Most of the time, skin manifestations can help in diagnosis.
3) It may affect overall health, so it is essential to maintain dryness and practice safe sex.

Reply Date: 2021/06/11

More Info


The presence of red spots on the glans and milky urethral gland fluid can be concerning and may indicate several underlying conditions. Based on your description, it seems you have already consulted with healthcare professionals and received some treatment. However, let’s delve deeper into the potential causes and solutions for your symptoms.

1. Causes of Red Spots on the Glans:
The red spots on the glans may be attributed to several factors. Common causes include:
- Fungal Infections: As you mentioned, a fungal infection was diagnosed. Fungi, particularly Candida species, can cause redness and irritation in the genital area. This is often exacerbated by moisture and friction during sexual activity or masturbation.

- Bacterial Infections: Although your tests returned negative for sexually transmitted infections (STIs), bacterial infections can still occur. The presence of milky urethral fluid could suggest a bacterial infection, possibly linked to the urethral glands.

- Irritation or Allergic Reactions: Products such as soaps, lotions, or condoms can cause irritation or allergic reactions, leading to redness and discomfort.

- Dermatological Conditions: Conditions such as balanitis (inflammation of the glans) or psoriasis can also present with red spots.

2. Milky Urethral Gland Fluid:
The change in the color and consistency of the urethral gland fluid from clear to milky can be indicative of an infection or inflammation. The milky appearance may suggest the presence of white blood cells or other inflammatory cells, which can occur in response to infection.
3. Confirming the Type of Fungal Infection:
To determine the specific type of fungal infection, a culture test can be performed. This involves taking a sample from the affected area and culturing it in a laboratory to identify the specific organism. Additionally, a KOH (potassium hydroxide) preparation can be done to visualize fungal elements directly under a microscope.

4. Impact of Not Collecting Midstream Urine:
Not collecting a midstream urine sample can indeed affect the accuracy of urine culture results. The midstream collection method is designed to minimize contamination from the urethra and surrounding skin, providing a more accurate representation of the urine in the bladder. If the sample is contaminated, it may lead to false-positive results for bacterial growth.

5. Recommendations for Management:
- Follow-Up with Healthcare Provider: Since your symptoms persist despite treatment, it is crucial to follow up with your healthcare provider. They may recommend further testing or a referral to a urologist or dermatologist for specialized care.

- Avoid Irritants: Until the underlying cause is identified, it may be beneficial to avoid potential irritants, such as scented soaps or lotions, and to practice good hygiene.

- Consider a Different Treatment Approach: If fungal treatment has not resolved the issue, your doctor may consider alternative antifungal medications or a longer course of treatment.

- Monitor Symptoms: Keep track of any changes in symptoms, including the frequency and severity of redness or changes in urethral fluid, and report these to your healthcare provider.

In conclusion, while your symptoms may be related to a fungal infection, other factors could also be contributing to your condition. It is essential to maintain open communication with your healthcare provider and to seek further evaluation if symptoms persist or worsen.

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