Medication Safety for Infants: Managing Eczema and Dermatitis - Pediatrics

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Neonatal Pharmacotherapy Consultation


Hello Doctor, my baby is currently over three months old.
At two months, I noticed red and itchy skin, and the doctor diagnosed it as atopic dermatitis, with seborrheic dermatitis on the scalp.
The doctor prescribed oral medication and a steroid cream.
I would like to ask if it is safe for such a young infant to take the following two oral medications? Once a day, taken before bedtime: 1.
Asumalife, one capsule at a time; 2.
Xyzal 5mg, half a tablet, ground into powder.
Are there any safety concerns regarding these medications? I found information online stating that Xyzal is not suitable for children under two years old, which raises some concerns since my baby is only over three months and cannot clearly express how they feel.
Thank you for taking the time to respond, Doctor.

Niming, 30~39 year old female. Ask Date: 2021/06/13

Dr. Xiao Kaiwen reply Pediatrics


If the severity of skin inflammation is significant and environmental control measures are well implemented yet still ineffective, medication can be considered for management.
Asumalife can be used for long-term control of allergic predisposition.
Xyzal is indeed less commonly used in children under two years of age.
Corticosteroid creams can be used for short-term treatment, but long-term use should be avoided whenever possible.

Reply Date: 2021/06/13

More Info


When it comes to managing eczema and dermatitis in infants, particularly those as young as three months, safety is a paramount concern for parents and healthcare providers alike. Your inquiry about the use of Asumalife and Xyzal in such young children is very relevant, especially given the potential risks associated with medications in this age group.

Firstly, it’s important to understand that eczema, or atopic dermatitis, is a common condition in infants and can manifest as red, itchy patches on the skin. Treatment often involves a combination of topical therapies, such as corticosteroids, and sometimes systemic medications, depending on the severity of the condition.
Asumalife is typically used for long-term management of allergic conditions. While it may be beneficial for controlling allergic symptoms, its safety in infants under six months is not well established. The use of any medication in very young children should be approached with caution, and it is advisable to consult with a pediatric dermatologist or allergist before starting such treatments.

Xyzal (Levocetirizine) is an antihistamine that is often used to relieve allergy symptoms, including itching associated with eczema. However, as you noted, it is generally not recommended for children under two years of age. The reason for this caution is that young infants may be more susceptible to the sedative effects of antihistamines, which can lead to respiratory depression or other adverse effects. Given that your child is only three months old, it would be prudent to avoid using Xyzal unless specifically prescribed by a healthcare provider who is aware of your child's medical history and current condition.

In managing eczema in infants, non-pharmacological approaches should be prioritized. These include:
1. Moisturization: Regularly applying emollients or moisturizers can help maintain skin hydration and barrier function. This is crucial in preventing flare-ups.

2. Bathing Practices: Short, lukewarm baths followed by immediate application of moisturizer can help soothe the skin. Avoiding harsh soaps and using gentle, fragrance-free products is advisable.

3. Avoiding Triggers: Identifying and avoiding potential irritants or allergens, such as certain fabrics, soaps, or foods, can help reduce flare-ups.

4. Environmental Control: Keeping the home environment cool and humid can also help manage symptoms, as heat and dryness can exacerbate eczema.

5. Topical Corticosteroids: If prescribed, these should be used as directed by a healthcare provider. They are effective in reducing inflammation but should be used judiciously to avoid potential side effects, especially with prolonged use.

6. Regular Follow-ups: Continuous monitoring by a pediatric dermatologist can help adjust treatment plans as needed and ensure that any medication used is appropriate for the child’s age and condition.

In conclusion, while medications like Asumalife and Xyzal may have their place in treating allergic conditions, their use in infants, especially those under two years of age, should be approached with caution. Always consult with a healthcare professional before starting any new medication, and focus on non-pharmacological strategies to manage eczema effectively. Your child's safety and well-being should always come first, and a tailored approach to treatment is essential.

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