Genital Warts: Treatment Progress and What to Expect - Dermatology

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Cauliflower (Condylomata Acuminata)


Hello Dr.
Lee, I discovered warts over a month ago and went to a large hospital outpatient clinic, where I was informed that non-essential surgeries cannot be performed at this time.
I subsequently underwent treatment with traditional Chinese medicine for a month, but the results have been unsatisfactory (the warts have only slightly reduced in size but remain around 1 cm, with sizes ranging from 0.3 to 1 cm, totaling about 7 to 8 lesions).
Since yesterday, I have been referred to another large hospital's dermatology department, where the doctor applied a topical solution (which was very irritating and caused a burning sensation) and prescribed me LedaDerm to apply.
The next day, when I showered, I noticed that the warts suddenly became very dry and hard, turning completely white, whereas they were originally dark brown.
During the application of LedaDerm at home, I did not experience any discomfort, stinging, or burning sensations.
Could you please tell me if this is a sign of improvement?

Xiao Chen, 30~39 year old female. Ask Date: 2021/06/16

Dr. Li Yufen reply Dermatology


Hello: You can observe whether the lesions of condylomata acuminata have decreased in size, fallen off, or reduced in number, and continue to follow up with dermatology for treatment.
Thank you!

Reply Date: 2021/06/16

More Info


Genital warts, also known as condylomata acuminata, are caused by certain strains of the human papillomavirus (HPV). They are typically characterized by small, flesh-colored or gray growths that can appear in the genital area, including the vulva, vagina, cervix, penis, scrotum, and anus. Understanding the treatment options and what to expect during the healing process is crucial for managing this condition effectively.

From your description, it seems that you have been undergoing treatment for your genital warts for over a month, initially with traditional Chinese medicine, which did not yield significant results. You then transitioned to a dermatology clinic where you received a topical treatment that caused a burning sensation. The application of a medication like "Lederme" (likely referring to a topical treatment such as imiquimod or another similar agent) is a common approach in managing genital warts.

The fact that the warts have changed in appearance—becoming dry, hard, and white—can indeed be a positive sign. This change often indicates that the treatment is working. Many topical treatments for genital warts work by inducing an inflammatory response in the tissue, which can lead to the destruction of the wart tissue. The whitening and hardening of the warts suggest that the cells are undergoing necrosis (cell death), which is a desired outcome in wart treatment.

However, it is essential to monitor the warts closely. While the initial response to treatment may be encouraging, it is not uncommon for warts to take time to resolve completely. The duration of treatment can vary widely among individuals, and some warts may require multiple treatment sessions or different modalities to achieve satisfactory results.

In terms of what to expect moving forward, here are some key points:
1. Follow-Up Appointments: Regular follow-up with your dermatologist is crucial. They can assess the response to treatment and make adjustments if necessary. If the warts do not continue to improve, alternative treatments such as cryotherapy (freezing), laser therapy, or surgical excision may be considered.

2. Side Effects: While topical treatments can be effective, they may also cause local irritation, redness, or discomfort. If you experience severe pain, swelling, or any signs of infection (such as pus or increased redness), you should contact your healthcare provider immediately.

3. Recurrence: Even after successful treatment, genital warts can recur because HPV can remain dormant in the body. It is essential to practice safe sex and communicate with sexual partners about HPV to reduce the risk of transmission.

4. Vaccination: If you have not already been vaccinated against HPV, consider discussing the HPV vaccine with your healthcare provider. The vaccine can protect against the strains of HPV that most commonly cause genital warts and cervical cancer.

5. Emotional Support: Dealing with genital warts can be emotionally challenging. It may be helpful to seek support from friends, family, or support groups to discuss your feelings and experiences.

In summary, the changes you are observing in your genital warts may indicate a positive response to treatment. Continue to follow your dermatologist's recommendations, and do not hesitate to reach out for further guidance or if you have concerns about your treatment progress. Remember that patience is key, as the healing process can take time.

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