Managing Dry Eye Disease: Concerns About Steroid Drops and Eye Pressure - Ophthalmology

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Medications for Dry Eye Syndrome


Hello, doctor.
Due to dry eye syndrome, my eyes often become inflamed and filled with blood vessels, so I have been using steroid eye drops for inflammation (for about a month) along with preservative-free artificial tears.
However, during a follow-up visit, it was found that my intraocular pressure had risen to 23, and the doctor advised me to discontinue the eye drops.
The doctor has prescribed Vitis eye gel for me.
Could you please tell me if this Vitis gel contains steroids or preservatives? Is it suitable for my current high intraocular pressure for long-term use? Additionally, does the gel contain any antibacterial agents, and is it safe for long-term use? Thank you, doctor.

Cherry, 30~39 year old female. Ask Date: 2021/06/20

Dr. Gao Pilin reply Ophthalmology


Hello Cherry: Vitis gel is steroid-free but contains preservatives.
It is currently available for use.
The gel does not contain antibiotics and can be applied 3-5 times a day for long-term use.
Online responses should only be used as a reference; if necessary, it is important to seek medical attention at a healthcare facility.
I hope to have the opportunity to serve you.
Best regards, Gao Pi-Lin.

Reply Date: 2021/06/20

More Info


Managing dry eye disease can be a complex issue, especially when it involves the use of steroid eye drops and concerns about elevated intraocular pressure (IOP). Your situation highlights the delicate balance between managing inflammation and avoiding potential complications such as increased eye pressure, which can lead to conditions like glaucoma.

Firstly, regarding the use of steroid eye drops, they are often prescribed for their potent anti-inflammatory properties, which can be beneficial for conditions like dry eye disease that may involve significant inflammation. However, long-term use of steroids can lead to increased IOP, as you have experienced. This is a well-documented side effect, and it is crucial to monitor IOP regularly when using these medications. In your case, the increase in IOP to 23 mmHg prompted your doctor to recommend discontinuing the steroid drops, which is a prudent decision to prevent potential damage to the optic nerve.

Now, concerning the use of Vidisic Gel, it is important to clarify that this product does not contain steroids. Vidisic Gel is a preservative-free artificial tear formulation that is designed to provide lubrication and relief for dry eyes. It is generally safe for long-term use, especially in patients with elevated IOP, as it does not contribute to further increases in eye pressure. The absence of preservatives is particularly beneficial for individuals with sensitive eyes or those who require frequent application of eye drops.

As for the presence of antimicrobial agents in the gel, it is essential to understand that while some formulations may include such agents to prevent contamination, Vidisic Gel is primarily intended for lubrication and does not typically contain antibiotics or other antimicrobial substances. Therefore, it can be used safely over an extended period without the risk of developing resistance or other complications associated with long-term antibiotic use.

In managing your dry eye disease, it is also advisable to incorporate other non-pharmacological strategies. These may include:
1. Environmental Modifications: Reducing exposure to wind and air conditioning, using humidifiers, and taking regular breaks from screens can help alleviate symptoms.

2. Dietary Adjustments: Increasing omega-3 fatty acids in your diet (found in fish oil and flaxseed) may help improve tear production and reduce inflammation.

3. Punctal Plugs: These are small devices inserted into the tear ducts to reduce tear drainage, thereby increasing the moisture on the surface of the eye.

4. Regular Follow-ups: Continuous monitoring of your IOP and overall eye health is essential, especially if you have a history of elevated pressure or other ocular conditions.

5. Consultation with Specialists: If your symptoms persist or worsen, consider seeking a second opinion from a cornea specialist or a glaucoma specialist who can provide tailored management strategies.

In summary, while steroid drops can be effective for managing inflammation associated with dry eye disease, their potential to elevate IOP necessitates careful monitoring and possibly discontinuation. Vidisic Gel is a safe alternative for long-term use in your case, and implementing additional strategies can further enhance your management of dry eye disease. Always communicate openly with your healthcare provider about your symptoms and any concerns you may have regarding your treatment plan.

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