Post-AZ Vaccine: Concerns About Chest Pain and Blood Clots - Cardiology

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After receiving the AZ vaccine?


Hello, Doctor He.
I received my first dose of the AZ vaccine on June 5, 2021, and experienced fever and body aches afterward.
Since then, I have had some mild shortness of breath and chest pain.
I am currently taking medication for diabetes and have a history of asthma.
On June 20, I noticed large red spots on my calves, with a few areas showing more pronounced bruising.
My feet feel a bit swollen, although they are not actually swollen, and my palms also feel puffy.
Should I be concerned about the possibility of a blood clot? Which specialty should I consult for an examination? Since receiving the vaccine on June 5 until now, June 21, 2021, I have not used any asthma medications or inhalers, as I am worried it might affect the vaccine's efficacy.
Thank you.

An An, 40~49 year old female. Ask Date: 2021/06/21

Dr. He Dongjin reply Cardiology


Hello, please visit the hematology department.
You should continue using your asthma medications and inhalers.
Changhua Hospital cares about you.

Reply Date: 2021/06/21

More Info


After receiving the AstraZeneca (AZ) vaccine, it is not uncommon for individuals to experience a range of side effects, including mild respiratory symptoms, muscle aches, and localized pain. However, the symptoms you describe—specifically chest pain, shortness of breath, and the appearance of bruising and redness in your legs—raise some important concerns that warrant careful consideration.

First, it is essential to understand that while many side effects of the AZ vaccine are mild and self-limiting, there are rare but serious adverse events associated with the vaccine, including Vaccine-Induced Immune Thrombotic Thrombocytopenia (VITT). This condition can lead to blood clots, particularly in unusual locations, and is characterized by low platelet counts. Symptoms of VITT can include severe headaches, abdominal pain, leg swelling, and visual disturbances, in addition to the symptoms you are experiencing.

Given your symptoms of chest pain and shortness of breath, along with the appearance of bruising and redness in your legs, it is crucial to seek medical attention promptly. These symptoms could potentially indicate the presence of a blood clot, particularly if they are accompanied by swelling or pain in the legs. The fact that you have diabetes and asthma may also complicate your situation, as these conditions can increase the risk of cardiovascular issues.

In terms of what type of specialist you should see, it would be advisable to consult with a healthcare provider who specializes in internal medicine or hematology. They can perform a thorough evaluation, which may include blood tests to check your platelet levels and assess for any signs of clotting disorders. Additionally, imaging studies such as an ultrasound of the legs or a CT scan of the chest may be necessary to rule out deep vein thrombosis (DVT) or pulmonary embolism (PE).

It is also important to note that if you have been experiencing persistent symptoms since your vaccination, you should not delay seeking medical care. While it is understandable to be concerned about the potential impact of medications on vaccine efficacy, your health and safety should take precedence. If you require asthma medication, it is crucial to discuss this with your healthcare provider, as they can help manage your symptoms while ensuring that you are protected against any potential complications from the vaccine.

In summary, while many individuals experience mild side effects after receiving the AZ vaccine, your symptoms of chest pain, shortness of breath, and leg changes are concerning and should be evaluated by a medical professional as soon as possible. Seeking care from an internal medicine or hematology specialist will allow for a comprehensive assessment and appropriate management of your symptoms. Remember, it is always better to err on the side of caution when it comes to your health.

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