RU486 Dosage: What You Need to Know for Safe Use - Obstetrics and Gynecology

More Info

---

RU486, also known as Mifepristone, is a medication used primarily for medical abortion. It is crucial to understand the proper dosage and administration to ensure its effectiveness and safety. Based on the information provided and general medical guidelines, I will clarify the dosage and usage of RU486, as well as address your concerns regarding its effectiveness when taken in a lower dosage.


Dosage and Administration
The standard dosage of RU486 for medical abortion is typically 600 mg, which is usually administered as three 200 mg tablets taken orally at once. This dosage has been established through extensive clinical studies and is considered effective for terminating early pregnancies, specifically those that are up to 10 weeks (70 days) gestational age.
In your case, where the ultrasound indicates a gestational age of approximately 5 weeks and 1 day, taking only one tablet (200 mg) is significantly below the recommended dosage. While there may be some anecdotal reports or variations in practice, the consensus in the medical community is that taking less than the standard dosage may not effectively induce abortion. It is essential to follow the prescribed dosage to ensure the medication works as intended.


Follow-Up with Cytotec
After taking RU486, it is common practice to follow up with another medication called Cytotec (Misoprostol). This medication is typically taken 24 to 48 hours after RU486 to help expel the pregnancy tissue from the uterus. The usual recommendation is to take 2 to 4 tablets of Cytotec, depending on the specific protocol your healthcare provider follows. In your case, your doctor has prescribed three tablets to be taken 48 hours after the RU486 dose, which aligns with standard practices.


Importance of Medical Supervision
It is crucial to have medical supervision throughout this process. Your healthcare provider will monitor your progress and may perform follow-up ultrasounds to ensure that the abortion is complete and that there are no complications. If you experience excessive bleeding, severe pain, or any other concerning symptoms, it is vital to seek medical attention immediately.


Potential Risks and Side Effects
While RU486 is generally safe when used correctly, there are potential side effects and risks associated with its use. Common side effects include:
1. Cramping and Bleeding: Most women will experience cramping and vaginal bleeding after taking RU486 and Cytotec. This is a normal part of the process, but if bleeding is excessively heavy (soaking through two or more pads in an hour for two consecutive hours), it requires immediate medical attention.

2. Nausea and Vomiting: Some women may experience gastrointestinal symptoms, which can be managed with over-the-counter medications.

3. Infection: There is a small risk of infection following a medical abortion. Signs of infection include fever, chills, and foul-smelling discharge.

4. Incomplete Abortion: In some cases, the abortion may not be complete, necessitating a follow-up procedure, such as a dilation and curettage (D&C).


Conclusion
In summary, it is essential to adhere to the recommended dosage of RU486 (600 mg) for it to be effective. Taking only one tablet may not induce the desired effect and could lead to complications. Always follow your healthcare provider's instructions and attend all follow-up appointments to ensure your health and safety throughout the process. If you have any concerns or questions about your treatment, do not hesitate to reach out to your healthcare provider for clarification and support.