Can active monitoring be implemented?
At the beginning of the year, I experienced difficulty urinating and underwent catheterization.
After about five months of medication, I again faced urinary difficulties, leading to catheterization and a prostatectomy.
My preoperative PSA level was 18.9, and postoperatively it dropped to 0.93.
The Gleason score was 6, with cancer cells occupying 0.03% of the resected area.
A digital rectal exam showed a smooth surface with no hard masses, and bone scans and ultrasound showed no metastasis.
I have hypertension and have been on medication for over seven years.
The doctor suggested that I could either pursue aggressive treatment or opt for active surveillance.
I am a bit confused; is it advisable to start with active surveillance for now?
DAVID, 60~69 year old female. Ask Date: 2021/07/07
Dr. Li Minghui reply Urology
Hello: Prostate cancer is quite unique; some cases may progress rapidly while others remain stable for many years.
There are various treatment options available if one chooses to pursue aggressive treatment, and the associated complications can vary significantly.
Therefore, it is important for individuals to carefully consider their options.
Active surveillance does not mean ignoring the condition; rather, it involves transitioning to active treatment if there are any changes.
Each person's situation is different, and factors such as age, overall health, and potential surgical complications must be taken into account.
Ultimately, the decision should be made by the patient.
Wishing you good health.
Reply Date: 2021/07/07
More Info
Navigating prostate health decisions, especially after a prostatectomy, can be quite challenging. Your situation involves several key factors that need to be considered when deciding between active monitoring and further treatment options.
First, let's break down your medical history and current status. You underwent a prostatectomy due to significant urinary difficulties, with a pre-operative PSA level of 18.9, which is notably elevated. Post-surgery, your PSA dropped to 0.93, indicating that the surgery was effective in removing the cancerous tissue. The Gleason score of 6 suggests a moderately differentiated cancer, which is generally considered less aggressive compared to higher scores. Additionally, the fact that only 0.03% of the resected tissue contained cancer cells is a positive sign, as is the absence of metastasis on both bone and ultrasound scans.
Given these factors, your physician's recommendation of either active treatment or active surveillance is not uncommon. Active surveillance is often recommended for patients with low-risk prostate cancer, particularly when the cancer appears to be contained and not aggressive. This approach involves regular monitoring of PSA levels, digital rectal exams, and possibly repeat biopsies to ensure that the cancer does not progress.
The decision to pursue active monitoring can be beneficial for several reasons. First, it allows you to avoid the potential side effects and complications associated with aggressive treatments such as radiation or hormone therapy, which can include fatigue, sexual dysfunction, and other health issues. Since you also have a history of hypertension, managing your overall health without the added burden of aggressive cancer treatment could be advantageous.
However, it is crucial to understand that active monitoring does not mean neglecting the cancer. It requires a commitment to regular follow-ups and being vigilant for any changes in your PSA levels or symptoms. If there is a significant rise in PSA or any new symptoms arise, you would then transition to active treatment. This approach is particularly suitable for patients who are older or have other health conditions that may complicate more aggressive treatments.
On the other hand, if you have concerns about the potential for cancer progression or if your PSA levels begin to rise significantly, discussing more aggressive treatment options with your healthcare provider would be prudent. Treatments such as radiation therapy or hormone therapy can be effective but come with their own sets of risks and side effects.
In conclusion, given your current low PSA level, the favorable pathology report, and the absence of metastasis, starting with active monitoring seems to be a reasonable approach. However, it is essential to maintain open communication with your healthcare provider, regularly assess your health status, and be prepared to make adjustments to your treatment plan as necessary. Always consider your personal comfort level with monitoring versus treatment, and ensure that your decisions align with your overall health goals and quality of life.
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