the Link Between Sinus Node Abnormalities and mRNA Vaccine Effects - Cardiology

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There have been cases of tachycardia symptoms due to abnormalities in the sinoatrial node following the administration of the mRNA vaccine (Moderna)?


Dear Dr.
Wu,
My father is 69 years old.
He is preparing to receive the Moderna vaccine, and I have a few questions to confirm before the vaccination.
There have been reports of myocarditis in young individuals after receiving mRNA vaccines abroad.
My father had an issue with his sinoatrial node ten years ago, which led to acute tachycardia.
This was mainly triggered by bending over or chest pressure.
The episodes are very infrequent; I remember him having two episodes since I was a child.
I am not very clear on the exact diagnosis, but during the emergency visits, the medical staff performed carotid artery compression and administered injections related to the heart.
Later, during follow-up visits, I heard the doctor mention information related to the sinoatrial node.
Here are the medications prescribed at that time for your reference:
1.
Propranolol 40 mg/tab (Cardolol 40 mg/tab)
2.
Diltiazem HCl 30 mg/tab (Herbesser)
I would like to understand if there is a potential correlation between myocarditis and the abnormal symptoms related to the sinoatrial node that could possibly trigger an episode.
Additionally, my father has symptoms related to hypertension and underwent successful surgery for kidney cancer five years ago.
Should he be able to receive the vaccine safely? Thank you.

Wu Bo-xian, 30~39 year old female. Ask Date: 2021/07/12

Dr. Wu Xueming reply Cardiology


1.
According to foreign data, cases of myocarditis have been reported following mRNA vaccine administration, primarily among young individuals, but the incidence is relatively low.
2.
Based on the current guidelines from the command center, as long as chronic diseases are well-managed and there are no physical discomforts, it is recommended to get vaccinated as soon as possible.

Reply Date: 2021/07/12

More Info


When considering the potential effects of mRNA vaccines, such as the Moderna vaccine, on individuals with pre-existing heart conditions, particularly those related to the sinus node, it is essential to understand both the nature of the vaccine and the specific medical history of the patient.

The mRNA vaccines work by introducing a small piece of messenger RNA that instructs cells to produce a harmless spike protein found on the surface of the SARS-CoV-2 virus. This process stimulates an immune response without causing the disease itself. However, there have been reports of myocarditis and pericarditis, particularly in younger males, following mRNA vaccination. These conditions involve inflammation of the heart muscle and the lining around the heart, respectively, and can lead to symptoms such as chest pain, shortness of breath, and feelings of having a fast-beating, fluttering, or pounding heart.

In your father's case, he has a history of sinus node issues that have led to episodes of acute tachycardia (rapid heart rate). The sinus node is responsible for initiating the electrical impulses that regulate heartbeats. If there are abnormalities in this area, it can lead to arrhythmias, which may be exacerbated by various factors, including stress, certain medications, or underlying health conditions.

The medications your father is currently taking, Propranolol and Diltiazem, are both used to manage heart rate and blood pressure. Propranolol is a beta-blocker that can help reduce heart rate and the workload on the heart, while Diltiazem is a calcium channel blocker that can also help control heart rate and lower blood pressure. These medications can be beneficial in managing symptoms related to sinus node dysfunction.

Regarding the concern about whether the mRNA vaccine could trigger myocarditis or exacerbate sinus node abnormalities, it is important to note that while there is a potential risk of myocarditis associated with mRNA vaccines, this risk is generally considered low, especially in older adults. Your father, being 69 years old, may not be at the same level of risk as younger individuals. Additionally, the benefits of vaccination, particularly in the context of the ongoing COVID-19 pandemic, often outweigh the potential risks, especially for individuals with underlying health conditions.

Given your father's history of sinus node issues and his previous episodes of tachycardia, it is crucial that he discusses his specific medical history with his healthcare provider before receiving the vaccine. The healthcare provider can evaluate his overall health status, consider any potential interactions with his current medications, and assess the risks versus benefits of vaccination in his particular case.

In summary, while there is a theoretical concern regarding the relationship between sinus node abnormalities and the effects of mRNA vaccines, the actual risk for your father may be relatively low, especially considering his age and the protective benefits of vaccination against severe COVID-19 outcomes. It is always best to have a thorough discussion with a healthcare professional who can provide personalized advice based on his complete medical history and current health status.

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