Nasopharyngeal Issues: Signs of Possible Cancer Recurrence - Otolaryngology

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Nasopharyngeal issues


My father received the biopsy report last week confirming a recurrence of oral cancer (this is his third occurrence of oral cancer).
He is currently waiting to be hospitalized for surgical treatment.
His oral condition shows granulation tissue near the lower left teeth, along with a hole, and there are wounds on his chin that are bleeding.
He suspects that the wounds may have connected.
He is experiencing pain from the mouth to the chin, as well as headaches (possibly due to continuous bleeding affecting his sleep or other reasons).
I would like to inquire about a situation he experienced over the past two days: while drinking water or milk without choking, he noticed that the liquid came out of his nose.
Could this be a sign of nasopharyngeal cancer, or is it possible that he did choke without realizing it? Thank you, doctor.

Sherry, 20~29 year old female. Ask Date: 2021/07/15

Dr. Zheng Jueyi reply Otolaryngology


Hello: The common issue may be related to the muscular valve between the oral cavity and the nasal cavity, which can become dysfunctional after surgery or radiation therapy, causing food to enter the nasal cavity.
This is mostly unrelated to nasopharyngeal cancer, but please have your physician confirm this during your follow-up visit.
Wishing you peace and good health.
Sincerely, Dr.
Cheng Jue-Yi, Director of the Department of Otolaryngology, Taoyuan Hospital, Ministry of Health and Welfare.

Reply Date: 2021/07/15

More Info


I'm sorry to hear about your father's situation. The recurrence of oral cancer, especially after multiple diagnoses, can be quite distressing for both the patient and the family. Let's address your concerns regarding the symptoms he is experiencing and their potential implications.

The presence of granulation tissue and ulceration near the lower left teeth, along with bleeding and pain in the jaw area, is concerning and could indicate local progression of the cancer. The fact that he is experiencing pain and has visible wounds suggests that there may be significant tissue involvement, which could complicate his recovery and treatment options.

One of the symptoms you mentioned is the regurgitation of liquids (water or milk) through the nose when drinking. This phenomenon, known as nasal regurgitation, can occur for several reasons. In the context of oral and potentially nasopharyngeal cancer, it could indicate a few things:
1. Anatomical Changes: If there is significant tissue damage or structural changes in the oral cavity or nasopharynx due to the cancer, it may lead to a disruption in the normal swallowing mechanism. This can result in liquids entering the nasal cavity instead of being directed down the esophagus.

2. Neurological Factors: Cancer and its treatments can affect the nerves that control swallowing. If these nerves are compromised, it may lead to improper coordination during swallowing, causing liquids to escape through the nose.

3. Aspiration: Although you mentioned that he did not choke, it is possible that he may have aspirated some liquid without realizing it. This can happen if the swallowing reflex is impaired, leading to liquids entering the airway instead of the esophagus.

4. Infection or Inflammation: The presence of ulcers and granulation tissue can also lead to inflammation, which may affect the normal function of the throat and nasal passages.

Given these symptoms, it is crucial to consult with his healthcare team as soon as possible. They may recommend imaging studies, such as a CT scan or MRI, to assess the extent of the disease and any potential complications. Additionally, a thorough evaluation by an ear, nose, and throat (ENT) specialist may be warranted to determine the cause of the nasal regurgitation and to assess the overall function of the swallowing mechanism.

In terms of treatment, if the cancer is confirmed to have recurred, the medical team will discuss the best options available, which may include surgery, radiation therapy, or chemotherapy, depending on the extent of the disease and the patient's overall health.

It's also important to manage his pain effectively and ensure he is receiving adequate nutrition, especially if swallowing is becoming increasingly difficult. Nutritional support, possibly through enteral feeding, may be necessary if oral intake becomes too challenging.

In summary, the symptoms your father is experiencing could be related to the recurrence of his oral cancer, but they could also be due to other factors such as anatomical changes or nerve involvement. It is essential to have a comprehensive evaluation by his medical team to determine the best course of action. Please ensure he receives the support he needs during this challenging time, both medically and emotionally.

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