Nasopharyngeal Cancer: Symptoms and Concerns - Otolaryngology

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Suspected nasopharyngeal carcinoma?


Hello, Dr.
Hsu: I had a severe cold in July and although I have recovered from the cold, I have been experiencing persistent yellow-green nasal discharge.
Since childhood, I have always had one nostril blocked while the other is clear.
Sometimes the nasal discharge is still yellow-green.
A kind doctor examined my nose and found significant swelling in the nasopharynx, raising concerns about nasopharyngeal carcinoma, which frightened me to tears.
Later, I researched some symptoms online and found that I match several of them: 1.
I occasionally experience tinnitus, but it doesn't happen frequently (only twice).
2.
Sometimes I cough up phlegm with blood streaks (initially the doctor said it was due to coughing too hard, but now I have completely changed my perspective).
3.
Most importantly, there is a family history; my father passed away from nasopharyngeal carcinoma, which increases my risk by 50 times compared to the general population.
My brother does not have these symptoms, but I do, and I am scheduled for a biopsy and EB virus testing.
I am very worried about developing this condition, and I have been experiencing sharp pain in my right kidney these past few days.

Yúyú, 20~29 year old female. Ask Date: 2006/08/20

Dr. Xu Jiazhen reply Otolaryngology


Hello: In response to your question, there is no need to be afraid.
Generally, swelling in the nasopharynx does not necessarily indicate cancer.
I would recommend waiting for the biopsy results before making any further determinations.

Reply Date: 2006/08/20

More Info


Understanding nasopharyngeal cancer (NPC) is crucial, especially given your family history and the symptoms you are experiencing. NPC is a type of head and neck cancer that originates in the nasopharynx, the area behind the nose and above the back of the throat. It is known to be associated with the Epstein-Barr virus (EBV) and has a higher prevalence in certain populations, particularly in Southeast Asia.


Symptoms of Nasopharyngeal Cancer
The symptoms of NPC can vary, but common signs include:
1. Nasal Congestion or Obstruction: This can manifest as difficulty breathing through the nose, which you mentioned experiencing. A persistent blockage, especially if accompanied by abnormal nasal discharge (like yellow-green mucus), can be a red flag.

2. Ear Symptoms: Ear fullness, hearing loss, or tinnitus (ear ringing) can occur due to the proximity of the nasopharynx to the Eustachian tubes, which connect the middle ear to the nasopharynx.

3. Sore Throat or Difficulty Swallowing: As the tumor grows, it can cause pain or discomfort in the throat, making swallowing difficult.

4. Coughing with Blood: Hemoptysis (coughing up blood) can be alarming and may indicate that the cancer has invaded nearby structures or caused irritation.

5. Lymph Node Swelling: Swollen lymph nodes in the neck are often one of the first signs of NPC, as the cancer can spread to these nodes.

6. Other Symptoms: These can include headaches, facial pain, and changes in vision if the tumor affects surrounding areas.


Concerns and Next Steps
Given your symptoms and family history, it is understandable that you are feeling anxious. The fact that your father had NPC increases your risk, as genetic factors can play a significant role in the development of this cancer. The presence of symptoms such as ear ringing, blood in sputum, and persistent nasal issues should be taken seriously.

1. Diagnostic Tests: You mentioned that you are scheduled for a biopsy and EBV testing. These are critical steps in confirming a diagnosis. The biopsy will provide histological evidence of cancer, while the EBV test can help assess the viral load, which is often elevated in NPC patients.

2. Management of Anxiety: It’s normal to feel anxious about potential diagnoses, especially with a family history. Consider discussing your concerns with a mental health professional or a support group for individuals facing similar health anxieties.

3. Pain Management: The pain you are experiencing in your kidney area could be unrelated to NPC, but it’s essential to discuss this with your healthcare provider. They may want to perform imaging studies to rule out other conditions.

4. Follow-Up Care: If diagnosed with NPC, treatment options typically include radiation therapy, chemotherapy, or a combination of both, depending on the stage of the cancer. Early-stage NPC has a good prognosis, especially with appropriate treatment.


Conclusion
While the symptoms you are experiencing can be concerning, they are not definitive proof of nasopharyngeal cancer. The upcoming tests will provide clarity. It is essential to maintain open communication with your healthcare team, who can guide you through the diagnostic process and any necessary treatment options. Remember to take care of your mental health during this time, as stress and anxiety can impact your overall well-being.

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