Post-Surgery Concerns for Giant Cell Tumor of the Spine: What to Expect? - Neurosurgery

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Postoperative issues following surgery for giant cell tumor of the spine?


I have a giant cell tumor at my lumbar spine L3.
I underwent surgery at the beginning of February, and the doctor mentioned that the tumor was removed cleanly.
He specifically referred to the surgical method called en bloc resection.
I am currently taking Denosumab to prevent recurrence.
I would like to know if the tumor grows back after stopping Denosumab, is that the end of it? It has been about 5.5 months since the surgery, and the doctor said it would take about a year for the bone to fully fuse.
We will check the status of the bone with a CT scan in August (after 6 months), as X-rays seem to show little.
Recently, for the past month or two, my lower back has been particularly sore, and sometimes my legs feel weak and fatigued, making it hard to sit still.
If the bone fuses completely, will my condition improve? The doctor prescribed me Rifampin to take one pill before bed.
I’m not sure if it’s psychological, but I feel like my back has improved a bit the next day.
At 23 years old, after undergoing fusion surgery, I feel like my back is ruined...
Here is the most recent X-ray, which also includes my upper body: https://drive.google.com/drive/folders/17BwuqDmvr5JNx0dE_Yrjxikiv1qbe1WY?usp=sharing

Ming, 20~29 year old female. Ask Date: 2021/07/20

Dr. Lai Zhaokang reply Neurosurgery


Hello, theoretically, as you wait for your spinal fusion, the stability should increase and your symptoms may improve.
I recommend that you consult with your surgical medical team.
Best wishes to you.

Reply Date: 2021/07/20

More Info


Post-surgery concerns for a giant cell tumor (GCT) of the spine can be quite complex, especially considering the nature of the tumor and the surgical interventions involved. It’s great to hear that your surgery was performed using the en bloc resection technique, which is often the preferred method for removing GCTs due to its potential to minimize recurrence by ensuring that the tumor is completely excised along with a margin of healthy tissue.

Regarding your concerns about Denosumab, it is important to understand that while this medication is effective in reducing the risk of recurrence for giant cell tumors, stopping it does not necessarily mean that the tumor will inevitably return. However, the risk of recurrence does increase once the medication is discontinued. It is crucial to maintain regular follow-ups with your healthcare provider to monitor for any signs of recurrence, especially during the first few years post-surgery when the risk is highest.

You mentioned that your doctor indicated it might take about a year for complete bone fusion to occur. This timeline is typical, as spinal fusion is a gradual process that can vary significantly among individuals. The fact that you are experiencing discomfort and weakness in your legs could be related to several factors, including the healing process, muscle atrophy from reduced activity during recovery, or even nerve irritation from the surgical site. As the bone heals and fuses, it is expected that your symptoms may improve, but this can take time.

The use of medications like Rifaximin (which you mentioned) can sometimes have a positive impact on your overall sense of well-being, but it’s essential to discuss any medication changes or concerns with your physician. They can provide insights into whether the improvement you feel is due to the medication or other factors.

As for your question about imaging, X-rays are often used to assess bone healing, but they may not always provide a complete picture of the fusion status. CT scans are generally more sensitive in detecting bone fusion and can give a clearer view of the healing process. It’s good that you have a follow-up CT scan scheduled; this will provide valuable information about your recovery.

In terms of lifestyle adjustments, it is advisable to engage in physical therapy as recommended by your healthcare team. A physical therapist can guide you through exercises that promote strength and flexibility, which can alleviate some of the discomfort you are experiencing. Additionally, maintaining a healthy lifestyle, including proper nutrition and hydration, can support your recovery.

In summary, while the concerns you have are valid, it is essential to maintain open communication with your healthcare team. They can help you navigate the complexities of your recovery, monitor for any signs of recurrence, and adjust your treatment plan as necessary. Remember, recovery from spinal surgery, especially after a giant cell tumor, is a journey that requires patience and support.

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